5qk5
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z1267773786== | |
- | + | <StructureSection load='5qk5' size='340' side='right' caption='[[5qk5]], [[Resolution|resolution]] 1.63Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5qk5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QK5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QK5 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K3J:N-ethyl-6-methylpyridazin-3-amine'>K3J</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qk5 OCA], [http://pdbe.org/5qk5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qk5 RCSB], [http://www.ebi.ac.uk/pdbsum/5qk5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qk5 ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN]] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Arrowsmith, C H]] | ||
+ | [[Category: Bountra, C]] | ||
+ | [[Category: Burgess-Brown, N]] | ||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
- | [[Category: | + | [[Category: Delft, F von]] |
- | + | ||
- | + | ||
[[Category: Dubianok, Y]] | [[Category: Dubianok, Y]] | ||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
+ | [[Category: Huber, K]] | ||
+ | [[Category: Krojer, T]] | ||
[[Category: Strain-Damerell, C]] | [[Category: Strain-Damerell, C]] | ||
- | [[Category: | + | [[Category: Wright, N]] |
- | [[Category: | + | [[Category: Hydrolase]] |
- | [[Category: | + | [[Category: Nudt5]] |
+ | [[Category: Pandda]] | ||
+ | [[Category: Sgc - diamond i04-1 fragment screening]] | ||
+ | [[Category: Xchemexplorer]] |
Revision as of 08:09, 19 December 2018
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z1267773786
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