6dcb
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA== | |
- | + | <StructureSection load='6dcb' size='340' side='right' caption='[[6dcb]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6dcb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DCB FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dcb OCA], [http://pdbe.org/6dcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dcb RCSB], [http://www.ebi.ac.uk/pdbsum/6dcb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dcb ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/MEPCE_HUMAN MEPCE_HUMAN]] S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.<ref>PMID:17643375</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Cascio, D]] | ||
+ | [[Category: Eichhorn, C]] | ||
+ | [[Category: Feigon, J]] | ||
+ | [[Category: Yang, Y]] | ||
+ | [[Category: 7sk rna]] | ||
+ | [[Category: Mepce]] | ||
+ | [[Category: Rna methyl transferase]] | ||
+ | [[Category: Transferase-rna complex]] |
Revision as of 08:18, 19 December 2018
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
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