6dcb

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'''Unreleased structure'''
 
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The entry 6dcb is ON HOLD until Paper Publication
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==Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA==
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<StructureSection load='6dcb' size='340' side='right' caption='[[6dcb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6dcb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DCB FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dcb OCA], [http://pdbe.org/6dcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dcb RCSB], [http://www.ebi.ac.uk/pdbsum/6dcb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dcb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MEPCE_HUMAN MEPCE_HUMAN]] S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.<ref>PMID:17643375</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Cascio, D]]
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[[Category: Eichhorn, C]]
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[[Category: Feigon, J]]
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[[Category: Yang, Y]]
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[[Category: 7sk rna]]
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[[Category: Mepce]]
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[[Category: Rna methyl transferase]]
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[[Category: Transferase-rna complex]]

Revision as of 08:18, 19 December 2018

Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA

6dcb, resolution 2.00Å

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