6hz3
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243G== | |
| - | + | <StructureSection load='6hz3' size='340' side='right' caption='[[6hz3]], [[Resolution|resolution]] 3.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hz3]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HZ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HZ3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6hz1|6hz1]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hz3 OCA], [http://pdbe.org/6hz3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hz3 RCSB], [http://www.ebi.ac.uk/pdbsum/6hz3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hz3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Delarue, M]] | [[Category: Delarue, M]] | ||
| - | [[Category: Hu, H | + | [[Category: Hu, H D]] |
| + | [[Category: Ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Pentameric transmembrane channel]] | ||
Revision as of 08:31, 19 December 2018
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243G
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