6i52
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Yeast RPA bound to ssDNA== | |
| - | + | <StructureSection load='6i52' size='340' side='right' caption='[[6i52]], [[Resolution|resolution]] 4.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6i52]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I52 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i52 OCA], [http://pdbe.org/6i52 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i52 RCSB], [http://www.ebi.ac.uk/pdbsum/6i52 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i52 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RFA3_YEAST RFA3_YEAST]] As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (By similarity). Stimulates the activity of a cognate strand exchange protein (SEP1). [[http://www.uniprot.org/uniprot/RFA1_YEAST RFA1_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication. [[http://www.uniprot.org/uniprot/RFA2_YEAST RFA2_YEAST]] Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aramayo, R J]] | ||
| + | [[Category: Yates, L A]] | ||
| + | [[Category: Zhang, X]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Dna binding]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Heterotrimer]] | ||
| + | [[Category: Ob-fold]] | ||
Revision as of 08:32, 19 December 2018
Yeast RPA bound to ssDNA
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