6ije

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'''Unreleased structure'''
 
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The entry 6ije is ON HOLD
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==Crystal structure of the type VI amidase immunity (Tai4) from Agrobacterium tumefaciens==
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<StructureSection load='6ije' size='340' side='right' caption='[[6ije]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ije]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ije FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ije OCA], [http://pdbe.org/6ije PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ije RCSB], [http://www.ebi.ac.uk/pdbsum/6ije PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ije ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The type VI secretion system (T6SS) comprises needle-shaped multisubunit complexes that play a role in the microbial defense systems of Gram-negative bacteria. Some Gram-negative bacteria harboring a T6SS deliver toxic effector proteins into the cytoplasm or periplasm of competing bacteria in order to lyse and kill them. To avoid self-cell disruption, these bacteria have cognate immunity proteins that inhibit their toxic effector proteins. T6SS amidase effector protein 4 (Tae4) and T6SS amidase immunity protein 4 (Tai4) are a representative of the toxic effector-immunity pairs of the T6SS. Here, the three-dimensional structures of Tai4 and the Tae4-Tai4 complex from Agrobacterium tumefaciens are reported at 1.55 and 1.9 A resolution, respectively. A structural comparison with other Tae4-Tai4 homologs revealed similarities and differences in the catalytic and inhibitory mechanisms among the Tae4 and Tai4 family proteins.
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Authors: Fukuhara, S., Nakane, T., Yamashita, K., Ishii, R., Ishitani, R., Nureki, O.
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Crystal structure of the Agrobacterium tumefaciens type VI effector-immunity complex.,Fukuhara S, Nakane T, Yamashita K, Ishii R, Ishitani R, Nureki O Acta Crystallogr F Struct Biol Commun. 2018 Dec 1;74(Pt 12):810-816. doi:, 10.1107/S2053230X18016369. Epub 2018 Nov 30. PMID:30511676<ref>PMID:30511676</ref>
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Description: Crystal structure of the type VI amidase immunity (Tai4) from Agrobacterium tumefaciens
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Nureki, O]]
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<div class="pdbe-citations 6ije" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Fukuhara, S]]
[[Category: Ishii, R]]
[[Category: Ishii, R]]
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[[Category: Ishitani, R]]
[[Category: Nakane, T]]
[[Category: Nakane, T]]
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[[Category: Nureki, O]]
[[Category: Yamashita, K]]
[[Category: Yamashita, K]]
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[[Category: Fukuhara, S]]
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[[Category: Antitoxin]]
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[[Category: Ishitani, R]]
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Revision as of 08:32, 19 December 2018

Crystal structure of the type VI amidase immunity (Tai4) from Agrobacterium tumefaciens

6ije, resolution 1.55Å

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