3c6g
From Proteopedia
(Difference between revisions)
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|PDB= 3c6g |SIZE=350|CAPTION= <scene name='initialview01'>3c6g</scene>, resolution 2.800Å | |PDB= 3c6g |SIZE=350|CAPTION= <scene name='initialview01'>3c6g</scene>, resolution 2.800Å | ||
|SITE= <scene name='pdbsite=AC1:Bcd+Binding+Site+For+Residue+B+800'>AC1</scene>, <scene name='pdbsite=AC2:Bcd+Binding+Site+For+Residue+B+801'>AC2</scene>, <scene name='pdbsite=AC3:Hem+Binding+Site+For+Residue+A+601'>AC3</scene>, <scene name='pdbsite=AC4:Hem+Binding+Site+For+Residue+B+601'>AC4</scene>, <scene name='pdbsite=AC5:Vd3+Binding+Site+For+Residue+B+700'>AC5</scene>, <scene name='pdbsite=AC6:Vd3+Binding+Site+For+Residue+A+701'>AC6</scene>, <scene name='pdbsite=AC7:Unx+Binding+Site+For+Residue+B+4'>AC7</scene>, <scene name='pdbsite=AC8:Unx+Binding+Site+For+Residue+B+5'>AC8</scene> and <scene name='pdbsite=AC9:Unx+Binding+Site+For+Residue+B+6'>AC9</scene> | |SITE= <scene name='pdbsite=AC1:Bcd+Binding+Site+For+Residue+B+800'>AC1</scene>, <scene name='pdbsite=AC2:Bcd+Binding+Site+For+Residue+B+801'>AC2</scene>, <scene name='pdbsite=AC3:Hem+Binding+Site+For+Residue+A+601'>AC3</scene>, <scene name='pdbsite=AC4:Hem+Binding+Site+For+Residue+B+601'>AC4</scene>, <scene name='pdbsite=AC5:Vd3+Binding+Site+For+Residue+B+700'>AC5</scene>, <scene name='pdbsite=AC6:Vd3+Binding+Site+For+Residue+A+701'>AC6</scene>, <scene name='pdbsite=AC7:Unx+Binding+Site+For+Residue+B+4'>AC7</scene>, <scene name='pdbsite=AC8:Unx+Binding+Site+For+Residue+B+5'>AC8</scene> and <scene name='pdbsite=AC9:Unx+Binding+Site+For+Residue+B+6'>AC9</scene> | ||
| - | |LIGAND= <scene name='pdbligand=BCD:BETA-CYCLODEXTRIN'>BCD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=VD3:(1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL'>VD3 | + | |LIGAND= <scene name='pdbligand=BCD:BETA-CYCLODEXTRIN'>BCD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=VD3:(1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL'>VD3</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= CYP2R1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= CYP2R1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c6g OCA], [http://www.ebi.ac.uk/pdbsum/3c6g PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c6g RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of CYP2R1 in complex with vitamin D3''' | '''Crystal structure of CYP2R1 in complex with vitamin D3''' | ||
| + | |||
| + | ==Disease== | ||
| + | Known disease associated with this structure: Rickets due to defect in vitamin D 25-hydroxylation OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608713 608713]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Tempel, W.]] | [[Category: Tempel, W.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| - | [[Category: BCD]] | ||
| - | [[Category: HEM]] | ||
| - | [[Category: UNX]] | ||
| - | [[Category: VD3]] | ||
[[Category: cytochrome p450]] | [[Category: cytochrome p450]] | ||
[[Category: disease mutation]] | [[Category: disease mutation]] | ||
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[[Category: vitamin d3]] | [[Category: vitamin d3]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:30:55 2008'' |
Revision as of 02:30, 31 March 2008
| |||||||
| , resolution 2.800Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | , , , , , , , and | ||||||
| Ligands: | , , , | ||||||
| Gene: | CYP2R1 (Homo sapiens) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of CYP2R1 in complex with vitamin D3
Disease
Known disease associated with this structure: Rickets due to defect in vitamin D 25-hydroxylation OMIM:[608713]
About this Structure
3C6G is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2OJD. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:30:55 2008
Categories: Homo sapiens | Single protein | Arrowsmith, C H. | Bochkarev, A. | Edwards, A M. | Loppnau, P. | Min, J. | Park, H. | Plotnikov, A N. | SGC, Structural Genomics Consortium. | Strushkevich, N V. | Sundstrom, M. | Tempel, W. | Weigelt, J. | Cytochrome p450 | Disease mutation | Drug metabolism | Endoplasmic reticulum | Heme | Iron | Membrane | Metal-binding | Microsome | Monooxygenase | Oxidoreductase | Sgc | Structural genomic | Structural genomics consortium | Vitamin d 25-hydroxylase | Vitamin d3
