5oc4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD R361A-R362A mutant== | |
| - | + | <StructureSection load='5oc4' size='340' side='right' caption='[[5oc4]], [[Resolution|resolution]] 1.71Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5oc4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OC4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oc4 OCA], [http://pdbe.org/5oc4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oc4 RCSB], [http://www.ebi.ac.uk/pdbsum/5oc4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oc4 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DUS2L_HUMAN DUS2L_HUMAN]] Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.<ref>PMID:15994936</ref> <ref>PMID:18096616</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bou-nader, C]] | ||
| + | [[Category: Hamdane, D]] | ||
| + | [[Category: Pecqueur, L]] | ||
| + | [[Category: Double-stranded rna-binding domain]] | ||
| + | [[Category: Rna binding protein]] | ||
Revision as of 08:10, 26 December 2018
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD R361A-R362A mutant
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