5yso
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434== | |
| - | + | <StructureSection load='5yso' size='340' side='right' caption='[[5yso]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yso]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YSO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=90C:4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol'>90C</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yso OCA], [http://pdbe.org/5yso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yso RCSB], [http://www.ebi.ac.uk/pdbsum/5yso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yso ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN]] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref> |
| - | [[Category: Song, J | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Bae, J H]] | ||
| + | [[Category: Chin, J W]] | ||
| + | [[Category: Cho, S J]] | ||
| + | [[Category: Jeon, Y H]] | ||
| + | [[Category: Song, J Y]] | ||
| + | [[Category: Yoon, H S]] | ||
| + | [[Category: Anaplastic thyroid cancer]] | ||
| + | [[Category: Estrogen-related receptor gamma]] | ||
| + | [[Category: Radioiodine therapy]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 08:11, 26 December 2018
Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434
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