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6isb
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==crystal structure of human CD226== | |
| - | + | <StructureSection load='6isb' size='340' side='right' caption='[[6isb]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6isb]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ISB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ISB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6isb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6isb OCA], [http://pdbe.org/6isb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6isb RCSB], [http://www.ebi.ac.uk/pdbsum/6isb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6isb ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CD226_HUMAN CD226_HUMAN]] Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).<ref>PMID:26755705</ref> <ref>PMID:8673704</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gao, G F]] | ||
| + | [[Category: Li, Y]] | ||
| + | [[Category: Qi, J]] | ||
| + | [[Category: Tan, S]] | ||
| + | [[Category: Wang, H]] | ||
| + | [[Category: Zhang, S]] | ||
| + | [[Category: Cd226]] | ||
| + | [[Category: Dnam-1]] | ||
| + | [[Category: Immune system]] | ||
Revision as of 08:25, 26 December 2018
crystal structure of human CD226
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Categories: Gao, G F | Li, Y | Qi, J | Tan, S | Wang, H | Zhang, S | Cd226 | Dnam-1 | Immune system
