Sandbox 1498
From Proteopedia
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==3BPU== | ==3BPU== | ||
| - | <StructureSection load='3BPU' size='350' side='right' caption='' scene=''> | + | <StructureSection load='3BPU' size='350' side='right' caption='' scene='80/805019/3bpu/1'> |
| - | 3BPU is a transferase found in Homo sapiens. It is the 3rd PDZ domain of human membrane associated guanylate kinase Q96QZ7, C677S and C709S double mutant. It is encoded by the MAGI1 gene. [https://www.rcsb.org/structure/3bpu | + | 3BPU is a transferase found in Homo sapiens. It is the 3rd PDZ domain of human membrane associated guanylate kinase Q96QZ7, C677S and C709S double mutant. It is encoded by the MAGI1 gene. [https://www.rcsb.org/structure/3bpu] |
== Function == | == Function == | ||
3BPU is involved in the cell signalisation. It may play a role as a scaffolding protein at cell-cell junctions. It may regulate acid-induced ASIC3<ref >http://www.rcsb.org/pdb/protein/Q9UHC3</ref> currents by modulating its expression at the cell surface through interacting with its PDZ domain. | 3BPU is involved in the cell signalisation. It may play a role as a scaffolding protein at cell-cell junctions. It may regulate acid-induced ASIC3<ref >http://www.rcsb.org/pdb/protein/Q9UHC3</ref> currents by modulating its expression at the cell surface through interacting with its PDZ domain. | ||
Revision as of 14:12, 30 December 2018
3BPU
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