This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox 1498
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
== Structure == | == Structure == | ||
| + | 3BPU is mainly made of components which lead to hydrophobic and polar (charged or uncharged) interactions [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpu] | ||
| + | |||
=== Primary structure === | === Primary structure === | ||
3BPU is a one chain structure of 88 amino-acids. There are 88 residues. [https://www.rcsb.org/structure/3BPU] | 3BPU is a one chain structure of 88 amino-acids. There are 88 residues. [https://www.rcsb.org/structure/3BPU] | ||
=== Secondary structure === | === Secondary structure === | ||
| - | 3BPU structure is composed of 10% of <scene name='80/805019/3bpu_helix/1'>helix</scene><scene name='80/805019/3bpu_helix/1'></scene> (1 left-handed alpha helix; 9 residues, mainly Leu, Met, His, Glu, Gln) and 40% of <scene name='80/805019/3bpu_sheets/1'>beta sheets</scene> (8 antiparallel strands; 36 residues, mainly Val, Ile, Trp). | + | 3BPU's structure is composed of 10% of <scene name='80/805019/3bpu_helix/1'>helix</scene><scene name='80/805019/3bpu_helix/1'></scene> (1 left-handed alpha helix; 9 residues, mainly Leu, Met, His, Glu, Gln) and 40% of <scene name='80/805019/3bpu_sheets/1'>beta sheets</scene> (8 antiparallel strands; 36 residues, mainly Val, Ile, Trp). |
=== Tertiary structure === | === Tertiary structure === | ||
| - | 3BPU is a membrane-associated protein. It interacts with the membrane thanks to its hydrophobic <scene name='80/805019/3bpu_sheets/1'>beta sheets</scene>. | + | 3BPU is a membrane-associated protein. It interacts with the membrane thanks to its hydrophobic <scene name='80/805019/3bpu_sheets/1'>beta sheets</scene> through hydrophobic interactions. |
| Line 34: | Line 36: | ||
== Interactions with ligands == | == Interactions with ligands == | ||
| - | + | 3BPU's ligands are two Zn atoms.[https://www.rcsb.org/3d-view/3BPU?preset=ligandInteraction&sele=ZN] The i<scene name='80/805019/3bpu_zn/1'>nteractions between the protein and its ligands</scene> are polar interactions. | |
| - | https://www.rcsb.org/3d-view/3BPU?preset=ligandInteraction&sele=ZN | + | His645 and Glu714 interact with a first Zn atom. |
| - | + | His699 and Val703 interact with a second Zn atom. | |
Revision as of 15:33, 30 December 2018
3BPU
| |||||||||||
