5z1t
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure Analysis of the BRD4(1)== | |
| - | + | <StructureSection load='5z1t' size='340' side='right' caption='[[5z1t]], [[Resolution|resolution]] 1.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5z1t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z1T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z1T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EFN:5-bromo-N-(6-hydroxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide'>EFN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z1t OCA], [http://pdbe.org/5z1t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z1t RCSB], [http://www.ebi.ac.uk/pdbsum/5z1t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z1t ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Song, M]] | ||
[[Category: Wang, C]] | [[Category: Wang, C]] | ||
[[Category: Xiang, Q]] | [[Category: Xiang, Q]] | ||
| - | [[Category: Song, M]] | ||
[[Category: Xu, Y]] | [[Category: Xu, Y]] | ||
| + | [[Category: Zhang, Y]] | ||
| + | [[Category: Bromodomain]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 06:06, 2 January 2019
Crystal Structure Analysis of the BRD4(1)
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Categories: Song, M | Wang, C | Xiang, Q | Xu, Y | Zhang, Y | Bromodomain | Transcription
