3l0v

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==Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket==
==Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket==
<StructureSection load='3l0v' size='340' side='right' caption='[[3l0v]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='3l0v' size='340' side='right' caption='[[3l0v]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAM17, CSVP, TACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAM17, CSVP, TACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM_17_endopeptidase ADAM 17 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.86 3.4.24.86] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM_17_endopeptidase ADAM 17 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.86 3.4.24.86] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l0v OCA], [http://pdbe.org/3l0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l0v RCSB], [http://www.ebi.ac.uk/pdbsum/3l0v PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l0v OCA], [http://pdbe.org/3l0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l0v RCSB], [http://www.ebi.ac.uk/pdbsum/3l0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l0v ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l0/3l0v_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l0/3l0v_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>

Revision as of 06:59, 2 January 2019

Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket

3l0v, resolution 1.75Å

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