Alpha-lytic protease
From Proteopedia
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'''Alpha-lytic protease''' (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region (residues 1-199) that catalyzes the folding of the protease. The second domain is the protease domain (residues 200-397).<ref>PMID:2611204</ref> | '''Alpha-lytic protease''' (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region (residues 1-199) that catalyzes the folding of the protease. The second domain is the protease domain (residues 200-397).<ref>PMID:2611204</ref> | ||
| - | *<scene name='55/551214/Cv/ | + | *<scene name='55/551214/Cv/4'>ALP protease domain and pro domain complex with benzenesulfonyl fluoride</scene>. Water molecules are shown as red spheres. |
| - | *<scene name='55/551214/Cv/ | + | *<scene name='55/551214/Cv/5'>Benzenesulfonyl fluoride binding site</scene> (PDB entry [[3pro]]).<ref>PMID:9808037</ref> |
</StructureSection> | </StructureSection> | ||
Revision as of 10:46, 6 January 2019
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3D Structures of alpha-lytic protease
Updated on 06-January-2019
References
- ↑ Bone R, Frank D, Kettner CA, Agard DA. Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry. 1989 Sep 19;28(19):7600-9. PMID:2611204
- ↑ Sauter NK, Mau T, Rader SD, Agard DA. Structure of alpha-lytic protease complexed with its pro region. Nat Struct Biol. 1998 Nov;5(11):945-50. PMID:9808037 doi:http://dx.doi.org/10.1038/2919
