Bungarotoxin
From Proteopedia
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| - | <StructureSection load='1hc9' size='450' side='right' scene='42/423360/Cv/ | + | <StructureSection load='1hc9' size='450' side='right' scene='42/423360/Cv/5' caption='α-Bungarotoxin (green) complex with peptide derived from acetylcholine receptor (yellow) and I- ion (PDB code [[1hc9]])'> |
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br /> | [[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br /> | ||
* '''α-BGT''' binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br /> | * '''α-BGT''' binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br /> | ||
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For toxins in Proteopedia see [[Toxins]]. | For toxins in Proteopedia see [[Toxins]]. | ||
| - | <scene name='42/423360/Cv/4'>Iod coordination site</scene> in α-Bungarotoxin (PDB code [[1hc9]]).<ref>PMID:11683996</ref> Water | + | <scene name='42/423360/Cv/4'>Iod coordination site</scene> in α-Bungarotoxin (PDB code [[1hc9]]).<ref>PMID:11683996</ref> Water molecule shown as red sphere. |
</StructureSection> | </StructureSection> | ||
== 3D Structures of Bungarotoxin == | == 3D Structures of Bungarotoxin == | ||
Revision as of 11:07, 8 January 2019
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3D Structures of Bungarotoxin
Updated on 08-January-2019
References
- ↑ Harel M, Kasher R, Nicolas A, Guss JM, Balass M, Fridkin M, Smit AB, Brejc K, Sixma TK, Katchalski-Katzir E, Sussman JL, Fuchs S. The binding site of acetylcholine receptor as visualized in the X-Ray structure of a complex between alpha-bungarotoxin and a mimotope peptide. Neuron. 2001 Oct 25;32(2):265-75. PMID:11683996
