Sandbox Reserved 1492
From Proteopedia
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{{Sandbox_Reserved_ESBS}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_Reserved_ESBS}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
- | == | + | ==Luciferase 4M46== |
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
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4M46's main function is to control a light-emitting reaction that occurs in fireflies. It is naturally present in ''Lampyris Turkestanicus'' and emits a green light. | 4M46's main function is to control a light-emitting reaction that occurs in fireflies. It is naturally present in ''Lampyris Turkestanicus'' and emits a green light. | ||
- | Luciferase 4M46's catalytic action involves helping D-Luciferin binding ATP, which is the first step of several reactions that lead a excited oxyluciferin to release light. This mechanism is essential for the reproduction of fireflies, but is also often use in genetic engineering as reporter gene. | + | Luciferase 4M46's catalytic action involves helping D-Luciferin binding ATP, which is the first step of several reactions that lead a excited oxyluciferin to release light. This mechanism is essential for the reproduction of fireflies, but is also often use in genetic engineering as reporter gene. As a reporter gene, it can be coupled with the gene of interest so that they are expressed at the same time. This way, if one observes fluorescence in a transgenic bacteria colony, they can deduce that the gene of interest is also expressed and validate their experiment. |
== Disease == | == Disease == |
Revision as of 17:00, 8 January 2019
This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543. |
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Luciferase 4M46
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644