Sandbox Reserved 1501
From Proteopedia
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== Function == | == Function == | ||
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| - | == Disease == | ||
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== Relevance == | == Relevance == | ||
| - | + | While the function of cytochrome b2 is to couple L-lactate dehydrogenation to cytochrome c reduction; the mutant ARG289LYS is changing the kinetics of the reactions. It is rising the K<sub>i</sub> of several components in comparison to the wild-type, while k<sub>cat</sub> and K<sub>M</sub> are also changed by a factor of 10. It changes also the induction by L-lactate. | |
| + | R289K-b(2) | ||
| + | eing a component of the mitochondrial inter membrane space | ||
== Structural highlights == | == Structural highlights == | ||
Revision as of 15:10, 10 January 2019
| This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543. |
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
