Sandbox Reserved 1487
From Proteopedia
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The thymidine kinase is located in human cells and virus cells like in Herpes simplex virus. In the human cells, it exists two forms called TK1 and TK2. | The thymidine kinase is located in human cells and virus cells like in Herpes simplex virus. In the human cells, it exists two forms called TK1 and TK2. | ||
- | This protein is a phosphotransferase enzyme that catalyses the reaction: | + | This protein is a [https://en.wikipedia.org/wiki/Phosphotransferase phosphotransferase] enzyme that catalyses the reaction: |
Deoxythymidine + ATP --> Deoxythymidine monophosphate + ADP | Deoxythymidine + ATP --> Deoxythymidine monophosphate + ADP | ||
Revision as of 13:41, 11 January 2019
This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543. |
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References
- ↑ https://tel.archives-ouvertes.fr/tel-00720223/document
- ↑ https://www.uniprot.org/uniprot/P03176
- ↑ https://www.rcsb.org/structure/1KI4
- ↑ https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=1KI4¶ms.chainEntityStrategyStr=all&forcePageForChain=A¶ms.annotationsStr=SCOP,Site%20Record,DSSP¶ms.chainsPerPage=2
- ↑ https://www.ebi.ac.uk/pdbe/entry/pdb/1ki4/analysis
- ↑ https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=1KI4¶ms.chainEntityStrategyStr=all&forcePageForChain=A¶ms.annotationsStr=SCOP,Site%20Record,DSSP¶ms.chainsPerPage=2
- ↑ https://www.rcsb.org/structure/1KI4
- ↑ https://www.ebi.ac.uk/pdbe/entry/pdb/1ki4/bound/SO4#3A
- ↑ https://www.ebi.ac.uk/pdbe/entry/pdb/1ki4/bound/BTD
- ↑ https://www.rcsb.org/structure/1KI4
- ↑ Champness JN, Bennett MS, Wien F, Visse R, Summers WC, Herdewijn P, de Clerq E, Ostrowski T, Jarvest RL, Sanderson MR. Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins. 1998 Aug 15;32(3):350-61. PMID:9715911
- ↑ https://www.who.int/fr/news-room/fact-sheets/detail/herpes-simplex-virus
- ↑ http://www.ipubli.inserm.fr/bitstream/handle/10608/1401/1999_5_625.pdf?sequence=4