6al3
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Lys49 PLA2 BPII derived from the venom of Protobothrops flavoviridis.== | |
| - | + | <StructureSection load='6al3' size='340' side='right' caption='[[6al3]], [[Resolution|resolution]] 2.57Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6al3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AL3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AL3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6al3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6al3 OCA], [http://pdbe.org/6al3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6al3 RCSB], [http://www.ebi.ac.uk/pdbsum/6al3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6al3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PA2B2_PROFL PA2B2_PROFL]] Snake venom phospholipase A2 (PLA2) that shows anticoagulant activities, strong myolytic activity, infiltration of polymorphonuclear cells, and edema in stromal tissues. Induces cell death of Jurkat cells in a concentration dependent manner. Shows a low phospholipase A2 activity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<ref>PMID:19463843</ref> <ref>PMID:2341374</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Protobothrops flavoviridis]] | ||
| + | [[Category: Kamata, S]] | ||
| + | [[Category: Matsui, T]] | ||
| + | [[Category: Oda-Ueda, N]] | ||
| + | [[Category: Ogawa, T]] | ||
| + | [[Category: Suzuki, A]] | ||
| + | [[Category: Tanaka, Y]] | ||
| + | [[Category: Nake venom]] | ||
| + | [[Category: Phospholipase a2]] | ||
| + | [[Category: Toxic component]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 12:00, 16 January 2019
Lys49 PLA2 BPII derived from the venom of Protobothrops flavoviridis.
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