6c2o
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of HCV NS3/4A protease variant Y56H in complex with danoprevir== | |
| - | + | <StructureSection load='6c2o' size='340' side='right' caption='[[6c2o]], [[Resolution|resolution]] 1.18Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6c2o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2o OCA], [http://pdbe.org/6c2o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2o RCSB], [http://www.ebi.ac.uk/pdbsum/6c2o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2o ProSAT]</span></td></tr> |
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Matthew, A N]] | ||
| + | [[Category: Schiffer, C A]] | ||
| + | [[Category: Drug resistance]] | ||
| + | [[Category: Hepatitis c virus]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Ns3/4a protease]] | ||
| + | [[Category: Protease inhibitor]] | ||
Revision as of 12:03, 16 January 2019
Crystal structure of HCV NS3/4A protease variant Y56H in complex with danoprevir
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