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6fgd
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Gephyrin E domain in complex with Artemether== | |
| - | + | <StructureSection load='6fgd' size='340' side='right' caption='[[6fgd]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fgd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FGD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FGD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=D8Z:Artemether'>D8Z</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fgd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fgd OCA], [http://pdbe.org/6fgd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fgd RCSB], [http://www.ebi.ac.uk/pdbsum/6fgd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fgd ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT]] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kasaragod, V B]] | ||
| + | [[Category: Schindelin, H]] | ||
| + | [[Category: Antimalarial compound]] | ||
| + | [[Category: Inhibitory neurotransmission]] | ||
| + | [[Category: Moonlighting protein]] | ||
| + | [[Category: Scaffolding protein]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 12:07, 16 January 2019
Crystal structure of Gephyrin E domain in complex with Artemether
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