6hso
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide== | |
- | + | <StructureSection load='6hso' size='340' side='right' caption='[[6hso]], [[Resolution|resolution]] 1.95Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6hso]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HSO FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3F7:1,1-BENZENE-1,4-DIYLBIS(1H-PYRROLE-2,5-DIONE)'>3F7</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hso OCA], [http://pdbe.org/6hso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hso RCSB], [http://www.ebi.ac.uk/pdbsum/6hso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hso ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT]] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Kasaragod, V B]] | ||
+ | [[Category: Schindelin, H]] | ||
+ | [[Category: Gephyrin]] | ||
+ | [[Category: Glycine receptor]] | ||
+ | [[Category: Inhibitory post synapse]] | ||
+ | [[Category: Moco biosynthesis]] | ||
+ | [[Category: Moonlighting protein]] | ||
+ | [[Category: Scaffolding protein]] | ||
+ | [[Category: Structural protein]] |
Revision as of 12:09, 16 January 2019
Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide
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