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Proteopedia's goal is to present structure/function information on 3D biomacromolecules in a user-friendly manner to a broad scientific audience.
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Its goal is to present this information in a user-friendly manner to a broad scientific audience as a free, collaborative 3D-encyclopedia of proteins & other molecules.
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Revision as of 09:05, 20 January 2019

ISSN 2310-6301

As life is more than 2D, Proteopedia helps to bridge the gap between 3D structure & function of biomacromolecules

Its goal is to present this information in a user-friendly manner to a broad scientific audience as a free, collaborative 3D-encyclopedia of proteins & other molecules.


Selected Pages Journals Education

Lifecycle of SARS-CoV-2

What happens if a SARS-CoV-2 coronavirus enters your lung? This molecular animation visualises how the virus particle can take over the host cell and turns it into a virus factory. Eventually, the host cell produces so many viral particles that it dies and releases numerous new virus particles. >>> Visit this page >>>

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Structure of Anticancer Ruthenium Half-Sandwich Complex Bound to Glycogen Synthase Kinase 3ß

G Atilla-Gocumen, L Di Costanzo, E Meggers. J Biol Inorg Chem. 2010 doi: 10.1007/s00775-010-0699-x
A crystal structure of an organometallic half-sandwich ruthenium complex bound to glycogen synthase kinase 3ß (GSK-3ß) reveals that the inhibitor binds to the ATP binding site via an induced fit mechanism utilizing several hydrogen bonds and hydrophobic interactions. Importantly, the metal is not involved in any direct interaction with the protein kinase but fulfills a purely structural role.

>>> Visit this I3DC complement >>>

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Virus Capsid Geometry

The Capsid of a virus is its outer shell or "skin". Viruses have evolved intricate and elegant ways to assemble capsid protein chains into complete, usually spherical capsids, often with icosahedral symmetry. Pictured is an extremely simplified model of a capsid, where a single enlarged atom represents each of the 360 protein chains in the capsid of the Simian Virus 40 (SV40), a member of a group of cancer-causing viruses that has been extensively researched for decades.

>>> See more animations and explanation >>>

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About Interactive 3D Complements - I3DCs

List of I3DCs

How to get an I3DC for your paper

Teaching strategies using Proteopedia

Examples of pages for teaching

How to add content to Proteopedia

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Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Jaime Prilusky

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