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Cytochrome P450

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Additional details on cytochrome P450 interactions with drugs see
Additional details on cytochrome P450 interactions with drugs see
*[[Drug Metabolism by CYP450 Enzymes]]<br />
*[[Drug Metabolism by CYP450 Enzymes]]<br />
-
*[[Montelukast]] - anticancer
+
*[[Montelukast]] - anti rhinitis
*[[Noxafil]] - antifungal drug which binds to CYP51.
*[[Noxafil]] - antifungal drug which binds to CYP51.

Revision as of 08:34, 23 January 2019

Cytochrome P450 CypC2 with heme C complex with warfarin (PDB entry 1og5)

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3D Structures of Cytochrome P450

Updated on 23-January-2019

References

  1. ↑ Danielson PB. The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr Drug Metab. 2002 Dec;3(6):561-97. PMID:12369887
  2. ↑ Williams PA, Cosme J, Ward A, Angove HC, Matak Vinkovic D, Jhoti H. Crystal structure of human cytochrome P450 2C9 with bound warfarin. Nature. 2003 Jul 24;424(6947):464-8. Epub 2003 Jul 13. PMID:12861225 doi:http://dx.doi.org/10.1038/nature01862

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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