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6cjs
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Candida albicans Hsp90 nucleotide binding domain in complex with AUY922== | |
| - | + | <StructureSection load='6cjs' size='340' side='right' caption='[[6cjs]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cjs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CJS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2GJ:5-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE'>2GJ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6cji|6cji]], [[6cjj|6cjj]], [[6cjl|6cjl]], [[6cjp|6cjp]], [[6cjr|6cjr]]</td></tr> |
| - | [[Category: Kirkpatrick, M | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjs OCA], [http://pdbe.org/6cjs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cjs RCSB], [http://www.ebi.ac.uk/pdbsum/6cjs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjs ProSAT]</span></td></tr> |
| - | [[Category: Pizarro, J | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HSP90_CANAL HSP90_CANAL]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kirkpatrick, M G]] | ||
| + | [[Category: Pizarro, J C]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Hsp90. atpase]] | ||
Revision as of 08:15, 30 January 2019
Candida albicans Hsp90 nucleotide binding domain in complex with AUY922
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