6f9k
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand== | |
| - | + | <StructureSection load='6f9k' size='340' side='right' caption='[[6f9k]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6f9k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F9K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D0Q:5-methyl-L-tryptophan'>D0Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f9k OCA], [http://pdbe.org/6f9k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f9k RCSB], [http://www.ebi.ac.uk/pdbsum/6f9k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f9k ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Hocker, B]] | [[Category: Hocker, B]] | ||
[[Category: Shanmugaratnam, S]] | [[Category: Shanmugaratnam, S]] | ||
| - | [[Category: Stiel, A | + | [[Category: Stiel, A C]] |
| + | [[Category: Ligand binding]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 08:19, 30 January 2019
Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
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