6ff8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of uncomplexed Rab32 in the active GTP-bound state at 2.13 Angstrom resolution== | |
| - | + | <StructureSection load='6ff8' size='340' side='right' caption='[[6ff8]], [[Resolution|resolution]] 2.13Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ff8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FF8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ff8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ff8 OCA], [http://pdbe.org/6ff8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ff8 RCSB], [http://www.ebi.ac.uk/pdbsum/6ff8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ff8 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RAB32_HUMAN RAB32_HUMAN]] Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.<ref>PMID:12186851</ref> <ref>PMID:21255211</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kecman, T]] | ||
| + | [[Category: Khan, A R]] | ||
| + | [[Category: Cell dynamic]] | ||
| + | [[Category: Gtp]] | ||
| + | [[Category: Rab]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Small gtpase]] | ||
| + | [[Category: Vesicle trafficking]] | ||
Revision as of 08:21, 30 January 2019
Crystal structure of uncomplexed Rab32 in the active GTP-bound state at 2.13 Angstrom resolution
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