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Immunodeficiency virus protease 3D structures

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Revision as of 20:16, 9 February 2019

Immunodeficiency virus protease 3D structures

Updated on 09-February-2019

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For additional information, see:

Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Immunodeficiency_virus_protease_3D_structures"

Category: Topic Page

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-==Your Heading Here (maybe something like 'Structure')==
+==Immunodeficiency virus protease 3D structures ==
-<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
-This is a default text for your page '''Immunodeficiency virus protease 3D structures'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
-== Function ==
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+{{#tree:id=OrganizedByTopic|openlevels=0|
-== Disease ==
+*
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+{{#tree:id=OrganizedByTopic|openlevels=0|
-== Relevance ==
+*HIV-I protease
-== Structural highlights ==
+**[[4yob]], [[4npu]], [[3u71]], [[2g69]], [[1lv1]], [[1odx]] – HIVP (mutant) – HIV-I virus<br />
+**[[2hvp]], [[1odw]], [[3phv]] – HIVP <br />
+**[[5uov]], [[5upz]], [[5ult]], [[5bry]], [[5bs4]], [[4mc1]], [[4mc2]], [[4mc6]], [[4mc9]], [[2q3k]], [[3th9]] [[5ult]] – HIVP (mutant) + sulfonamide inhibitor <br />
+**[[3qrm]], [[3qpj]], [[3qbf]], [[3ckt]], [[3qro]], [[3qrs]], [[4gb2]] – HIVP (mutant) + pyrrolidine inhibitor <br />
+**[[1hte]], [[1htf]], [[1htg]] – HIVP + penicillin inhibitor <br />
+**[[5kqx]], [[5kqy]], [[5kqz]], [[5kr0]], [[5kr1]], [[5kr2]], [[5b18]], [[4ll3]], [[4jec]], [[3tkg]], [[3tkw]], [[3tl9]] – HIVP + drug<br />
+**[[5t8h]], [[5e5j]], [[5e5k]], [[4yoa]], [[4q5m]], [[3swj]], [[4npt]], [[4qgi]], [[3s43]], [[3s45]], [[3s53]], [[3s54]], [[3s56]], [[3d1x]], [[3cyw]], [[3cyx]], [[3d1z]], [[3d20]], [[3bvb]], [[2r5p]], [[2r5q]], [[2hs1]], [[2hs2]], [[2q5k]], [[2nmy]], [[2nmz]], [[2nnk]], [[2nnp]], [[2fxe]], [[2o4l]], [[2o4s]], [[2fgu]], [[2fgv]], [[3so9]], [[3spk]], [[3k4v]], [[1fb7]], [[2fxd]], [[2fxe]], [[3el4]], [[3el5]], [[3el9]], [[2z54]] – HIVP (mutant) + drug<br />
+**[[4u7q]], [[4u7v]], [[4u8w]], [[4i8z]], [[4i8w]], [[3t11]], [[4fe6]], [[4a6b]], [[4a6c]], [[4dfg]], [[4dqb]], [[3gga]], [[3ggx]], [[2pwc]], [[2pwr]], [[2qnn]], [[2fde]], [[3kfr]], [[3kfs]], [[3tlh]], [[1hiv]], [[1hps]], [[1hpv]], [[1hvi]], [[1hvj]], [[1hvk]], [[1hvl]], [[1sbg]], [[1sh9]], [[1upj]], [[1w5v]], [[2uxz]], [[2uy0]], [[2zga]], [[3dcr]], [[3s85]], [[3zps]], [[3zpt]], [[3zpu]], [[4phv]], [[9hvp]], [[1c6x]], [[1c6y]], [[1c6z]], [[1c70]], [[1hxb]], [[2a4f]], [[1hos]], [[5ivq]], [[5ivr]], [[5ivs]], [[5ivt]], [[2upj]] – HIVP + inhibitor <br />
+**[[5jfp]], [[5jfu]], [[5jg1]], [[5kao]], [[5dgu]], [[5dgw]], [[5agz]], [[5ah6]],  [[5ah8]], [[5ah9]], [[5aha]], [[5ahb]], [[5ahc]], [[5ah7]], [[4cpq]], [[4cpr]], [[4cps]], [[4cpt]], [[4cpu]], [[4cpw]], [[4cpx]], [[4coe]], [[4cp7]], [[4m8x]], [[4m8y]], [[3vf5]], [[3vf7]], [[3vfa]], [[3vfb]], [[4a4q]], [[3tof]], [[3tog]], [[3toh]], [[4djo]], [[4djp]], [[4djq]], [[4djr]], [[3sa3]], [[3sa4]], [[3sa5]], [[3sa6]], [[3sa7]], [[3sa8]], [[3sa9]], [[3saa]], [[3sab]], [[3sac]], [[4dqc]], [[4dqe]], [[4dqf]], [[4dqg]], [[4dqh]], [[3qrm]], [[3qro]], [[3qrs]],  [[3qp0]], [[3qpj]], [[3qn8]], [[3qih]], [[3qbf]], [[3qaa]], [[3h5b]], [[3dk1]], [[3djk]], [[2r43]], [[3d1y]], [[2qci]], [[2qd6]], [[2qd7]], [[2qd8]], [[2qhy]], [[2qhz]], [[2qi1]], [[2qi7]], [[2z4o]], [[3bva]], [[3bxr]], [[3bxs]], [[2q54]], [[2j9j]], [[2j9k]], [[2je4]], [[2hc0]], [[2psu]], [[2psv]], [[2i0a]], [[2i0d]], [[2f3k]], [[2idw]], [[2ien]], [[2ieo]], [[2hb3]], [[1zbg]], [[2f80]], [[2f81]], [[2f8g]], [[2azc]], [[2a1e]], [[2fdd]], [[2aoc]], [[2aod]], [[2aoe]], [[1w5w]], [[1w5x]], [[1w5y]], [[3i7e]], [[1bdq]], [[1bwa]], [[1bwb]], [[1gnm]], [[1gnn]], [[1mrx]], [[1msn]], [[1sgu]], [[1t7i]], [[2pk5]], [[2pk6]], [[2r38]], [[2r3t]], [[3fx5]], [[3h5b]], [[3i6o]], [[3kdb]], [[3kdc]], [[3kdd]], [[3ok9]], [[3qaa]], [[3st5]], [[4hdb]], [[4hdf]], [[4hdp]], [[4he9]], [[4heg]], [[4kb9]], [[4zip]], [[5cok]], [[5con]], [[5coo]], [[5cop]], [[2xye]], [[2xyf]], [[4zls]], [[1axa]], [[1hef]], [[1heg]], [[1a8k]], [[1aaq]] – HIVP (mutant) + inhibitor <br />
+**[[2zye]] – HIVP (mutant) + inhibitor - neutron<br />
-This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
+*HIV-I protease complex with peptide
-</StructureSection>
+**[[4tvg]], [[5hvp]] – HIVP + pepstatin peptide<br />
-== References ==
+**[[4f73]], [[4f74]], [[4f75]], [[4f76]], [[4ep2]], [[4ep3]], [[4epj]], [[4eq0]], [[4eqj]] – HIVP + substrate peptide<br />
-<references/>
+**[[4fae]], [[4faf]], [[2fns]], [[2fnt]], [[1f7a]], [[1kj4]], [[1kj7]], [[1kjf]], [[1kjg]], [[1kjh]], [[1tsq]], [[1tsu]], [[2aof]], [[2aog]], [[2aoh]], [[5yrs]], [[3d3t]] – HIVP (mutant) + substrate peptide<br />
+**[[4qj2]], [[4qj6]], [[4qj7]], [[4qj8]], [[4qj9]], [[4qja]], [[4fl8]], [[4flg]], [[4fm6]], [[4e43]], [[3b7v]], [[3b80]], [[2nxd]], [[2nxl]], [[2nxm]], [[4gzf]] – HIVP (mutant) + peptide<br />
+**[[1zsr]], [[1hbv]] – HIVP + peptidomimetic inhibitor<br />
+**[[1lzq]], [[1z8c]], [[1zbg]], [[1zj7]], [[1zpk]] – HIVP (mutant) + peptidomimetic inhibitor<br />
+**[[4i3s]], [[4i3r]] – HIVP Gp120 + antibody<br />
+*Drug resistant HIV-I protease
+**[[4z4x]], [[4z50]], [[5t2e]], [[4q1w]], [[4q1x]], [[4q1y]], [[4qlh]], [[4nkk]], [[3uf3]], [[2avm]], [[2avo]], [[2avq]], [[2avs]], [[2avv]], [[3oq7]], [[3oqa]], [[3oqd]], [[3pj6]], [[1rpi]], [[1rq9]], [[1tw7]] – HIVP (mutant) <br />
+**[[4ye3]], [[4yhq]], [[4rvi]], [[4rvx]], [[4njs]], [[4j54]], [[4j55]], [[3t3c]], [[3r0w]], [[3r0y]], [[2p3a]], [[2p3b]], [[2p3c]], [[2p3d]], [[1bv7]], [[1hvs]], [[1n49]] – HIVP (mutant) + inhibitor <br />
+**[[4rvj]] – HIVP + drug<br />
+**[[5t2z]], [[4l1a]], [[4njt]], [[4nju]], [[4njv]], [[4j5j]], [[4eyr]], [[3ttp]], [[3ucb]], [[3ufn]], [[3u7s]], [[3uhl]], [[3ekp]], [[3ekq]], [[3ekt]], [[3ekv]], [[3ekw]], [[3eky]], [[3el0]], [[3el5]], [[3el9]], [[3em3]], [[3em4]], [[3em6]], [[1rv7]], [[1t7j]], [[3ggu]] – HIVP (mutant) + drug<br />
+**[[4obd]], [[4obf]], [[4obg]], [[4obh]], [[4obj]], [[4obk]] – HIVP (mutant) + peptide<br />
+**[[1fej]], [[1ff0]], [[1fff]], [[1ffi]], [[1fg6]], [[1fg8]], [[1fgc]] – HIVP (mutant) + substrate analog<br />
+*HIV-I protease complex at the top of the flap
+**[[4ej8]], [[4ejl]] – HIVP (mutant) + indole derivative<br />
+**[[4k4q]] – HIVP (mutant) + bromobenzoate derivative<br />
+**[[4k4r]] – HIVP (mutant) + bromonaphthoate derivative<br />
+**[[4ejd]], [[4ejk]] – HIVP + pepstatin peptide + indole derivative<br />
+**[[4tvh]] – HIVP + inhibitor + indole derivative<br />
+*Synthetic HIV-I protease
+**[[2o40]] – syHIVP - synthetic<br />
+**[[3hau]], [[3haw]], [[3nwq]], [[3nwx]], [[3nxe]], [[3nxn]], [[3nyg]], [[4hvp]] – syHIVP + inhibitor <br />
+**[[3hlo]], [[3ia9]], [[3fsm]], [[3gi0]], [[3iaw]], [[3ka2]], [[3i2l]], [[7hvp]], [[8hvp]] – syHIVP (mutant) + inhibitor <br />
+*HIV-II
+**[[3ebz]] – HIVP + drug<br />
+**[[3ec0]], [[3ecg]], [[1ida]], [[1idb]], [[3ec0]], [[3ecg]], [[1ivq]] – HIVP + inhibitor<br />
+**[[3upj]], [[4upj]], [[1ivp]], [[6upj]], [[5upj]] – HIVP (mutant) + inhibitor <br />
+**[[5cay]] – HIVP + CD4<br />
+*FIV (Feline Immunodeficiency Virus)
+**[[1b11]], [[5fiv]], [[6fiv]], [[4fiv]], [[2fiv]], [[3fiv]], [[1fiv]], [[3tlh]] – FIVP + inhibitor – cat immunodeficiency virus <br />
+**[[2hah]] – FIVP (mutant) + inhibitor <br />
+**[[3ogp]], [[3ogq]] – FIVP (mutant) + drug<br />
+*SIV (Simian Immunodeficiency Virus)
+**[[1sip]] – SIVP – monkey immunodeficiency virus<br />
+**[[1az5]] – SIVP (mutant) <br />
+**[[2siv]], [[1qbz]] – SIVP Gp41 <br />
+**[[2bf1]] – SIVP Gp120 <br />
+**[[1tcw]], [[2sam]], [[1siv]] – SIVP + inhibitor <br />
+**[[1ytg]], [[1yth]], [[1yti]], [[1ytj]] – SIVP + peptide <br />
+}}
+==Additional Resources==
+For additional information, see:
+<br />
+* [[Human Immunodeficiency Virus]]
+* [http://cdn.rcsb.org/pdb101/learn/resources/structural-biology-of-hiv/index.html Structural Biology of HIV], an interactive Flash graphic of the virion with explanations of its components.
+}}
+[[Category:Topic Page]]

Immunodeficiency virus protease 3D structures

From Proteopedia

Revision as of 20:16, 9 February 2019

Immunodeficiency virus protease 3D structures

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