Cell division protein

From Proteopedia

Revision as of 10:06, 11 February 2019

spinqualitylabelsall models Ftsz complex with GTP (PDB code 1w5b) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Cell Division Protein FtsZ (Ftsz) is the prokaryotic homolog of tubulin. Ftsz assembles into a ring at the site of the septum in bacterial cell division. Ftsz stands for Filamenting Temperature-Sensitive mutant Z. Ftsz can bind GTP and hydrolyze it to GDP[1]. ZapA, ZapB, ZapC, ZapD (Z-Associated Protein) are regulators which modulate the dynamics of the FtsZ ring at midcell division site[2]. Structural highlights (PDB code 1w5b). Water molecules are shown as red spheres.

3D Structures of cell division protein

Updated on 11-February-2019

References

1. ↑ Oliva MA, Cordell SC, Lowe J. Structural insights into FtsZ protofilament formation. Nat Struct Mol Biol. 2004 Dec;11(12):1243-50. Epub 2004 Nov 21. PMID:15558053 doi:10.1038/nsmb855
2. ↑ Durand-Heredia JM, Yu HH, De Carlo S, Lesser CF, Janakiraman A. Identification and characterization of ZapC, a stabilizer of the FtsZ ring in Escherichia coli. J Bacteriol. 2011 Mar;193(6):1405-13. doi: 10.1128/JB.01258-10. Epub 2011 Jan 7. PMID:21216995 doi:http://dx.doi.org/10.1128/JB.01258-10