Choline kinase

(Difference between revisions)

Revision as of 10:29, 13 February 2019

Structure of human choline kinase α2 complex with phosphocholine (PDB code 2ckq).

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Updated on 13-February-2019

↑ Malito E, Sekulic N, Too WC, Konrad M, Lavie A. Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine. J Mol Biol. 2006 Nov 24;364(2):136-51. Epub 2006 Sep 3. PMID:17007874 doi:10.1016/j.jmb.2006.08.084

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 == Structural highlights ==
-The choline binds to CK in a <scene name='59/593958/Cv/3'>deep hydrophobic groove</scene> (PDB code [[2ckq]]; {{Template:ColorKey_Hydrophobic}},  {{Template:ColorKey_Polar}}) and the <scene name='59/593958/Cv/4'>ADP binds in a cleft</scene> (PDB code [[2ckp]]). <ref>PMID:17007874</ref>
+The choline binds to CK in a <scene name='59/593958/Cv/5'>deep hydrophobic groove</scene> (PDB code [[2ckq]]; {{Template:ColorKey_Hydrophobic}},  {{Template:ColorKey_Polar}}) and the <scene name='59/593958/Cv/6'>ADP binds in a cleft</scene> (PDB code [[2ckp]]). <ref>PMID:17007874</ref>
 </StructureSection>