This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6akf
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin== | |
| - | + | <StructureSection load='6akf' size='340' side='right' caption='[[6akf]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6akf]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AKF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ake|6ake]]</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6akf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6akf OCA], [http://pdbe.org/6akf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6akf RCSB], [http://www.ebi.ac.uk/pdbsum/6akf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6akf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CLD3_MOUSE CLD3_MOUSE]] Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<ref>PMID:10508613</ref> [[http://www.uniprot.org/uniprot/ELTB_CLOPF ELTB_CLOPF]] This enterotoxin is responsible for many cases of a mild type of food poisoning. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Fujiyoshi, Y]] | [[Category: Fujiyoshi, Y]] | ||
[[Category: Irie, K]] | [[Category: Irie, K]] | ||
[[Category: Nakamura, S]] | [[Category: Nakamura, S]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Membrane protein-toxin complex]] | ||
| + | [[Category: Tight junction]] | ||
Revision as of 06:36, 21 February 2019
Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin
| |||||||||||
