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6av1
From Proteopedia
(Difference between revisions)
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<StructureSection load='6av1' size='340' side='right' caption='[[6av1]], [[Resolution|resolution]] 2.45Å' scene=''> | <StructureSection load='6av1' size='340' side='right' caption='[[6av1]], [[Resolution|resolution]] 2.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6av1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AV1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6av1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AV1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W69:6-(2-{3-[3-(dimethylamino)propyl]-5-fluorophenyl}ethyl)-4-methylpyridin-2-amine'>W69</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W69:6-(2-{3-[3-(dimethylamino)propyl]-5-fluorophenyl}ethyl)-4-methylpyridin-2-amine'>W69</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6aur|6aur]], [[6aut|6aut]], [[6auq|6auq]], [[6aus|6aus]], [[6auz|6auz]], [[6auy|6auy]], [[6av0|6av0]], [[6av2|6av2]], [[6av6|6av6]], [[6av7|6av7]], [[6auu|6auu]], [[6auv|6auv]], [[6auw|6auw]], [[6aux|6aux]], [[6av3|6av3]], [[6av4|6av4]], [[6av5|6av5]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6aur|6aur]], [[6aut|6aut]], [[6auq|6auq]], [[6aus|6aus]], [[6auz|6auz]], [[6auy|6auy]], [[6av0|6av0]], [[6av2|6av2]], [[6av6|6av6]], [[6av7|6av7]], [[6auu|6auu]], [[6auv|6auv]], [[6auw|6auw]], [[6aux|6aux]], [[6av3|6av3]], [[6av4|6av4]], [[6av5|6av5]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NOS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6av1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6av1 OCA], [http://pdbe.org/6av1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6av1 RCSB], [http://www.ebi.ac.uk/pdbsum/6av1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6av1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6av1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6av1 OCA], [http://pdbe.org/6av1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6av1 RCSB], [http://www.ebi.ac.uk/pdbsum/6av1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6av1 ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 6av1" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6av1" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Nitric Oxide Synthase|Nitric Oxide Synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Li, H]] | [[Category: Li, H]] | ||
[[Category: Poulos, T L]] | [[Category: Poulos, T L]] | ||
[[Category: Nitric oxide synthase inhibitor complex heme enzyme]] | [[Category: Nitric oxide synthase inhibitor complex heme enzyme]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 07:43, 21 February 2019
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(Dimethylamino)propyl)-5-fluorophenethyl)-4-methylpyridin-2-amine
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