Dehalogenase

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== Structural highlights ==
== Structural highlights ==
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In the fluoroacetate dehalogenase complex with halide, the <scene name='59/594596/Cv/4'>iodide is seen in the active site cavity between two tryptophans</scene> (in cyan).<ref>PMID:8369276</ref>
+
In the fluoroacetate dehalogenase complex with halide, the <scene name='59/594596/Cv/5'>iodide is seen in the active site cavity between two tryptophans</scene> (in cyan).<ref>PMID:8369276</ref>
</StructureSection>
</StructureSection>

Revision as of 10:54, 21 February 2019

Structure of haloalkane dehalogenase complex with I- ion (purple) (PDB code 2edc).

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3D structures of dehalogenase

Updated on 21-February-2019


References

  1. Koudelakova T, Chovancova E, Brezovsky J, Monincova M, Fortova A, Jarkovsky J, Damborsky J. Substrate specificity of haloalkane dehalogenases. Biochem J. 2011 Apr 15;435(2):345-54. doi: 10.1042/BJ20101405. PMID:21294712 doi:http://dx.doi.org/10.1042/BJ20101405
  2. Verschueren KH, Kingma J, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW. Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry. 1993 Sep 7;32(35):9031-7. PMID:8369276

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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