5zm7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5zm7 is ON HOLD until Paper Publication
+
==Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution==
-
 
+
<StructureSection load='5zm7' size='340' side='right' caption='[[5zm7]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5zm7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZM7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZM7 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zm7 OCA], [http://pdbe.org/5zm7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zm7 RCSB], [http://www.ebi.ac.uk/pdbsum/5zm7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zm7 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/OSBL1_HUMAN OSBL1_HUMAN]] Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193).<ref>PMID:16176980</ref> <ref>PMID:17428193</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Dong, J]]
 +
[[Category: Wang, J]]
 +
[[Category: Wu, J W]]
 +
[[Category: Complex]]
 +
[[Category: Lipid]]
 +
[[Category: Lipid transport]]
 +
[[Category: Transporter]]

Revision as of 15:12, 27 February 2019

Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution

5zm7, resolution 3.40Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5zm7"
Personal tools