6cfi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion== | |
| - | + | <StructureSection load='6cfi' size='340' side='right' caption='[[6cfi]], [[Resolution|resolution]] 3.36Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cfi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CFI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=T64:(6-4)PHOTOPRODUCT'>T64</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfi OCA], [http://pdbe.org/6cfi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cfi RCSB], [http://www.ebi.ac.uk/pdbsum/6cfi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfi ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RAD4_YEAST RAD4_YEAST]] Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. [[http://www.uniprot.org/uniprot/RAD23_YEAST RAD23_YEAST]] Plays a central role both in proteasomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Jeffrey, P D]] | ||
| + | [[Category: Min, J]] | ||
| + | [[Category: Dna binding protein-dna complex]] | ||
| + | [[Category: Dna damage repair]] | ||
| + | [[Category: Nucleotide excision repair]] | ||
| + | [[Category: Ultraviolet]] | ||
| + | [[Category: Xeroderma pigmentosum]] | ||
| + | [[Category: Xpc]] | ||
Revision as of 15:14, 27 February 2019
Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion
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