6muj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Formylglycine generating enzyme bound to copper== | |
| - | + | <StructureSection load='6muj' size='340' side='right' caption='[[6muj]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6muj]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MUJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formylglycine-generating_enzyme Formylglycine-generating enzyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.3.7 1.8.3.7] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6muj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6muj OCA], [http://pdbe.org/6muj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6muj RCSB], [http://www.ebi.ac.uk/pdbsum/6muj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6muj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FGE_STRCO FGE_STRCO]] Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile.<ref>PMID:18390551</ref> <ref>PMID:25931126</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Formylglycine-generating enzyme]] | ||
| + | [[Category: Appel, M J]] | ||
| + | [[Category: Bertozzi, C]] | ||
| + | [[Category: Lafrance-Vanasse, J]] | ||
| + | [[Category: Tainer, J A]] | ||
| + | [[Category: Tsai, C L]] | ||
| + | [[Category: Copper oxidase]] | ||
| + | [[Category: Formylglycine]] | ||
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: Metalloenzyme]] | ||
Revision as of 15:29, 27 February 2019
Formylglycine generating enzyme bound to copper
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