6ncm

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'''Unreleased structure'''
 
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The entry 6ncm is ON HOLD until Paper Publication
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==Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence==
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<StructureSection load='6ncm' size='340' side='right' caption='[[6ncm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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Authors: Rogers, J.M., Jarrett, S.M., Seegar, T.C., Waters, C.T., Hallworth, A.N., Blacklow, S.C., Bulyk, M.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ncm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NCM FirstGlance]. <br>
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Description: Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nce|6nce]]</td></tr>
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[[Category: Bulyk, M.L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ncm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ncm OCA], [http://pdbe.org/6ncm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ncm RCSB], [http://www.ebi.ac.uk/pdbsum/6ncm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ncm ProSAT]</span></td></tr>
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[[Category: Seegar, T.C]]
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</table>
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[[Category: Rogers, J.M]]
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== Function ==
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[[Category: Jarrett, S.M]]
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[[http://www.uniprot.org/uniprot/FOXN3_HUMAN FOXN3_HUMAN]] Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).<ref>PMID:16102918</ref>
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[[Category: Waters, C.T]]
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== References ==
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[[Category: Hallworth, A.N]]
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<references/>
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[[Category: Blacklow, S.C]]
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__TOC__
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</StructureSection>
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[[Category: Blacklow, S C]]
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[[Category: Bulyk, M L]]
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[[Category: Hallworth, A N]]
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[[Category: Jarrett, S M]]
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[[Category: Rogers, J M]]
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[[Category: Seegar, T C]]
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[[Category: Waters, C T]]
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[[Category: Dna binding protein]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Dna binding transcription factor activity]]
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[[Category: Forkhead]]
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[[Category: Regulation of transcription dna templated]]
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[[Category: Sequence specific dna binding]]

Revision as of 15:30, 27 February 2019

Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence

6ncm, resolution 2.70Å

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