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6nce
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence== | |
| - | + | <StructureSection load='6nce' size='340' side='right' caption='[[6nce]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6nce]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NCE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nce OCA], [http://pdbe.org/6nce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nce RCSB], [http://www.ebi.ac.uk/pdbsum/6nce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nce ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FOXN3_HUMAN FOXN3_HUMAN]] Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).<ref>PMID:16102918</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Blacklow, S C]] | ||
| + | [[Category: Bulyk, M L]] | ||
| + | [[Category: Hallworth, A N]] | ||
| + | [[Category: Jarrett, S M]] | ||
| + | [[Category: Rogers, J M]] | ||
| + | [[Category: Seegar, T C]] | ||
| + | [[Category: Waters, C T]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Dna binding protein-dna complex]] | ||
| + | [[Category: Dna binding transcription factor activity]] | ||
| + | [[Category: Forkhead]] | ||
| + | [[Category: Regulation of transcription dna templated]] | ||
| + | [[Category: Sequence specific dna binding]] | ||
Revision as of 15:30, 27 February 2019
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence
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