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3zwo
From Proteopedia
(Difference between revisions)
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==Crystal structure of ADP ribosyl cyclase complexed with reaction intermediate== | ==Crystal structure of ADP ribosyl cyclase complexed with reaction intermediate== | ||
<StructureSection load='3zwo' size='340' side='right' caption='[[3zwo]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3zwo' size='340' side='right' caption='[[3zwo]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3zwo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3zwo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZWO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZWO FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G2Q:GUANOSINE+DIPHOSPHATE+RIBOSE'>G2Q</scene>, <scene name='pdbligand=NGD:3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]PYRIDINIUM'>NGD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G2Q:GUANOSINE+DIPHOSPHATE+RIBOSE'>G2Q</scene>, <scene name='pdbligand=NGD:3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]PYRIDINIUM'>NGD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r0s|1r0s]], [[3zwn|3zwn]], [[1lbe|1lbe]], [[1r16|1r16]], [[3zwx|3zwx]], [[3zwm|3zwm]], [[3zwv|3zwv]], [[3zwy|3zwy]], [[3zwp|3zwp]], [[3zww|3zww]], [[1r15|1r15]], [[1r12|1r12]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r0s|1r0s]], [[3zwn|3zwn]], [[1lbe|1lbe]], [[1r16|1r16]], [[3zwx|3zwx]], [[3zwm|3zwm]], [[3zwv|3zwv]], [[3zwy|3zwy]], [[3zwp|3zwp]], [[3zww|3zww]], [[1r15|1r15]], [[1r12|1r12]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zwo RCSB], [http://www.ebi.ac.uk/pdbsum/3zwo PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwo OCA], [http://pdbe.org/3zwo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zwo RCSB], [http://www.ebi.ac.uk/pdbsum/3zwo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zwo ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3zwo" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Aplca]] |
[[Category: Graeff, R]] | [[Category: Graeff, R]] | ||
[[Category: Hao, Q]] | [[Category: Hao, Q]] | ||
Revision as of 16:19, 27 February 2019
Crystal structure of ADP ribosyl cyclase complexed with reaction intermediate
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Categories: Aplca | Graeff, R | Hao, Q | Kotaka, M | Lee, H C | Zhang, L H | Cd38 | Hydrolase | Hydrolysis | Nad | Substrate specificity
