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3zxb

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Revision as of 16:57, 27 February 2019

Wild type single insulin-like growth factor binding domain protein (SIBD-1) from Cupiennius salei

Structural highlights

3zxb is a 4 chain structure with sequence from American wandering spider. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	3zxc
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[SIBD1_CUPSA] Has a role in the innate immune system.^[1]

Publication Abstract from PubMed

Cupiennius salei single insulin-like growth factor binding domain protein (SIBD-1) is an 8.6 kDa Cys-, Pro-, and Gly-rich protein, discovered in the hemocytes of the Central American hunting spider Cupiennius salei. SIBD-1 exhibits high sequence similarity to the N-terminal domain of the insulin-like growth factor-binding protein superfamily and has been reported to play an important role in the spider's immune system. Here, the recombinant expression as well as the elucidation of the three dimensional structure of recombinant SIBD-1 and the characterization of the sugar moiety at Thr2 of native SIBD-1 is described in detail. Proteins 2012. (c) 2012 Wiley-Liss, Inc.

Structural and Biochemical Characterization of Native and Recombinant Single Insulin-like Growth Factor-Binding Domain Protein (SIBD-1) from the Central American Hunting Spider Cupiennius salei (Ctenidae).,Trachsel C, Widmer C, Kampfer U, Buhr C, Baumann T, Kuhn-Nentwig L, Schurch S, Schaller J, Baumann U Proteins. 2012 May 24. doi: 10.1002/prot.24119. PMID:22622866^[2]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Kuhn-Nentwig L, Largiader CR, Streitberger K, Chandru S, Baumann T, Kampfer U, Schaller J, Schurch S, Nentwig W. Purification, cDNA structure and biological significance of a single insulin-like growth factor-binding domain protein (SIBD-1) identified in the hemocytes of the spider Cupiennius salei. Insect Biochem Mol Biol. 2011 Nov;41(11):891-901. doi:, 10.1016/j.ibmb.2011.08.003. Epub 2011 Aug 26. PMID:21888974 doi:http://dx.doi.org/10.1016/j.ibmb.2011.08.003
↑ Trachsel C, Widmer C, Kampfer U, Buhr C, Baumann T, Kuhn-Nentwig L, Schurch S, Schaller J, Baumann U. Structural and Biochemical Characterization of Native and Recombinant Single Insulin-like Growth Factor-Binding Domain Protein (SIBD-1) from the Central American Hunting Spider Cupiennius salei (Ctenidae). Proteins. 2012 May 24. doi: 10.1002/prot.24119. PMID:22622866 doi:10.1002/prot.24119

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3zxb"

@@ Line 3: / Line 3: @@
 <StructureSection load='3zxb' size='340' side='right' caption='[[3zxb]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3zxb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupsa Cupsa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZXB FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3zxb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/American_wandering_spider American wandering spider]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZXB FirstGlance]. <br>
 </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zxc|3zxc]]</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zxb OCA], [http://pdbe.org/3zxb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zxb RCSB], [http://www.ebi.ac.uk/pdbsum/3zxb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zxb ProSAT]</span></td></tr>
@@ Line 22: / Line 22: @@
 __TOC__
 </StructureSection>
-[[Category: Cupsa]]
+[[Category: American wandering spider]]
 [[Category: Baumann, U]]
 [[Category: Widmer, C]]

3zxb

From Proteopedia

Revision as of 16:57, 27 February 2019

Wild type single insulin-like growth factor binding domain protein (SIBD-1) from Cupiennius salei

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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