3zwx
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose== | ==Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose== | ||
<StructureSection load='3zwx' size='340' side='right' caption='[[3zwx]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='3zwx' size='340' side='right' caption='[[3zwx]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3zwx]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3zwx]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZWX FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AV1:[(2R,3S,4R,5R)-5-(6-AMINO-8-BROMO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+[(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>AV1</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AV1:[(2R,3S,4R,5R)-5-(6-AMINO-8-BROMO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+[(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>AV1</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r0s|1r0s]], [[3zwn|3zwn]], [[1lbe|1lbe]], [[1r16|1r16]], [[3zwo|3zwo]], [[3zwp|3zwp]], [[1r12|1r12]], [[1r15|1r15]], [[3zwv|3zwv]], [[3zwy|3zwy]], [[3zww|3zww]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r0s|1r0s]], [[3zwn|3zwn]], [[1lbe|1lbe]], [[1r16|1r16]], [[3zwo|3zwo]], [[3zwp|3zwp]], [[1r12|1r12]], [[1r15|1r15]], [[3zwv|3zwv]], [[3zwy|3zwy]], [[3zww|3zww]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zwx RCSB], [http://www.ebi.ac.uk/pdbsum/3zwx PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwx OCA], [http://pdbe.org/3zwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zwx RCSB], [http://www.ebi.ac.uk/pdbsum/3zwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zwx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 12: | Line 13: | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Aplca]] |
[[Category: Graeff, R]] | [[Category: Graeff, R]] | ||
[[Category: Hao, Q]] | [[Category: Hao, Q]] | ||
Revision as of 17:06, 27 February 2019
Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose
| |||||||||||
Categories: Aplca | Graeff, R | Hao, Q | Kotaka, M | Lee, H C | Zhang, L H | Cd38 | Hydrolase | Substrate specificity
