Adhesin
From Proteopedia
(Difference between revisions)
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*<scene name='70/705684/Cv/3'>Galactose binding site</scene>. Water molecules are shown as red spheres. | *<scene name='70/705684/Cv/3'>Galactose binding site</scene>. Water molecules are shown as red spheres. | ||
*<scene name='70/705684/Cv/5'>Tert-butyl formate/Acetate binding site</scene>. | *<scene name='70/705684/Cv/5'>Tert-butyl formate/Acetate binding site</scene>. | ||
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| + | == 3D Structures of adhesin == | ||
| + | [[Adhesin 3D structures]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of adhesin == | == 3D Structures of adhesin == | ||
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**[[4b4p]], [[4bwo]] – EcF18 lectin domain <BR /> | **[[4b4p]], [[4bwo]] – EcF18 lectin domain <BR /> | ||
**[[4auu]], [[1uwf]], [[1tr7]], [[5fwr]] – EcAdh FimH lectin domain <BR /> | **[[4auu]], [[1uwf]], [[1tr7]], [[5fwr]] – EcAdh FimH lectin domain <BR /> | ||
| - | **[[5mca]], [[5fx3]] – EcAdh FimH lectin domain (mutant) <BR /> | + | **[[5mca]], [[5fx3]], [[5fs5]] – EcAdh FimH lectin domain (mutant) <BR /> |
**[[5afo]] – EcAdh LF82 <BR /> | **[[5afo]] – EcAdh LF82 <BR /> | ||
**[[6aow]] – EcAdh FMLH lectin domain <BR /> | **[[6aow]] – EcAdh FMLH lectin domain <BR /> | ||
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**[[3zk8]], [[3zk9]], [[3zka]] – SpPsaA (mutant)<br /> | **[[3zk8]], [[3zk9]], [[3zka]] – SpPsaA (mutant)<br /> | ||
**[[3u4k]] – Adh lectin domain – ''Klebsiella pneumoniae''<BR /> | **[[3u4k]] – Adh lectin domain – ''Klebsiella pneumoniae''<BR /> | ||
| + | **[[6h1q]] – Adh – ''Proteus mirabilis'' <br /> | ||
*Fimbrial adhesion complexes | *Fimbrial adhesion complexes | ||
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**[[4w6w]], [[4w6x]], [[4w6y]] – EcF18 lectin domain + nanobody <BR /> | **[[4w6w]], [[4w6x]], [[4w6y]] – EcF18 lectin domain + nanobody <BR /> | ||
**[[4j3o]] – EcAdh FimH + FimG + FimC + FimF + FimD <BR /> | **[[4j3o]] – EcAdh FimH + FimG + FimC + FimF + FimD <BR /> | ||
| + | **[[6e14]], [[6e15]] – EcAdh FimH + FimG + FimC + FimF + FimD - Cryo EM<BR /> | ||
**[[3rfz]], [[1ze3]] – EcAdh FimH + FimC + FimD <BR /> | **[[3rfz]], [[1ze3]] – EcAdh FimH + FimC + FimD <BR /> | ||
**[[1qun]], [[1klf]], [[1kiu]] – EcAdh FimH + FimC <BR /> | **[[1qun]], [[1klf]], [[1kiu]] – EcAdh FimH + FimC <BR /> | ||
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**[[6aox]] – EcAdh FMLD lectin domain + TF antigen <BR /> | **[[6aox]] – EcAdh FMLD lectin domain + TF antigen <BR /> | ||
**[[6aro]] – EcAdh FMLH lectin domain + quinoline derivative <BR /> | **[[6aro]] – EcAdh FMLH lectin domain + quinoline derivative <BR /> | ||
| - | **[[5muc]], [[5l4y]], [[5l4x]], [[5l4w]], [[5l4v]], [[5l4u]], [[5l4t]], [[5jcq]], [[5jcr]], [[5f2f]], [[5f3f]], [[5abz]], [[4xo8]], [[4x5p]], [[4x5q]], [[4x5r]], [[4lov]], [[4css]], [[4cst]], [[4att]], [[4auj]], [[4auy]], [[4av0]], [[4av4]], [[4av5]], [[4avh]], [[4avi]], [[4avj]], [[4avk]], [[3zl1]], [[3zl2]], [[2vco]] – EcAdh FimH lectin domain + mannoside derivative <BR /> | + | **[[5muc]], [[5l4y]], [[5l4x]], [[5l4w]], [[5l4v]], [[5l4u]], [[5l4t]], [[5jcq]], [[5jcr]], [[5f2f]], [[5f3f]], [[5abz]], [[4xo8]], [[4x5p]], [[4x5q]], [[4x5r]], [[4lov]], [[4css]], [[4cst]], [[4att]], [[4auj]], [[4auy]], [[4av0]], [[4av4]], [[4av5]], [[4avh]], [[4avi]], [[4avj]], [[4avk]], [[3zl1]], [[3zl2]], [[2vco]], [[6gtx]], [[6gty]] – EcAdh FimH lectin domain + mannoside derivative <BR /> |
**[[5cgb]] – EcAdh FimH lectin domain + galactitol <BR /> | **[[5cgb]] – EcAdh FimH lectin domain + galactitol <BR /> | ||
**[[5ab1]], [[4x50]] – EcAdh FimH + mannoside derivative <BR /> | **[[5ab1]], [[4x50]] – EcAdh FimH + mannoside derivative <BR /> | ||
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**[[3d9x]] – Adh A – ''Bartonella henselae'' <BR /> | **[[3d9x]] – Adh A – ''Bartonella henselae'' <BR /> | ||
**[[2lwb]] – Adh WI-1 – ''Ajellomyces dermatitidis'' <BR /> | **[[2lwb]] – Adh WI-1 – ''Ajellomyces dermatitidis'' <BR /> | ||
| - | **[[5my7]] – | + | **[[5my7]] – NmAdh residues 1-124 – ''Neisseria meningitidis'' <BR /> |
| + | **[[6eun]] – NmAdh residues 24-170<BR /> | ||
| + | **[[6eup]] – NmAdh residues 24-170 (mutant)<BR /> | ||
| + | **[[6gq4]] – Adh residues 83-185 – ''Neisseria gonorheae''<BR /> | ||
}} | }} | ||
Revision as of 09:33, 3 March 2019
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3D Structures of adhesin
Updated on 03-March-2019
References
- ↑ Klemm P, Schembri MA. Bacterial adhesins: function and structure. Int J Med Microbiol. 2000 Mar;290(1):27-35. PMID:11043979 doi:http://dx.doi.org/10.1016/S1438-4221(00)80102-2
- ↑ Nishiyama M, Ishikawa T, Rechsteiner H, Glockshuber R. Reconstitution of pilus assembly reveals a bacterial outer membrane catalyst. Science. 2008 Apr 18;320(5874):376-9. doi: 10.1126/science.1154994. Epub 2008 Mar, 27. PMID:18369105 doi:http://dx.doi.org/10.1126/science.1154994
- ↑ Wizemann TM, Adamou JE, Langermann S. Adhesins as targets for vaccine development. Emerg Infect Dis. 1999 May-Jun;5(3):395-403. doi: 10.3201/eid0503.990310. PMID:10341176 doi:http://dx.doi.org/10.3201/eid0503.990310
- ↑ Bao R, Nair MK, Tang WK, Esser L, Sadhukhan A, Holland RL, Xia D, Schifferli DM. Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis. Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1065-70. doi:, 10.1073/pnas.1212431110. Epub 2012 Dec 31. PMID:23277582 doi:10.1073/pnas.1212431110
