Alkaline phosphatase

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*<scene name='47/471754/Cv/4'>Zn cluster</scene>.
*<scene name='47/471754/Cv/4'>Zn cluster</scene>.
*<scene name='47/471754/Cv/5'>Mg+2 coordination site</scene>.
*<scene name='47/471754/Cv/5'>Mg+2 coordination site</scene>.
 +
 +
== 3D Structures of alkaline phosphatase ==
 +
[[Alkaline phosphatase 3D structures]]
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</StructureSection>
</StructureSection>
== 3D Structures of alkaline phosphatase ==
== 3D Structures of alkaline phosphatase ==
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**[[3e2d]] – ALP + Zn + Mg – ''Vibrio''<br />
**[[3e2d]] – ALP + Zn + Mg – ''Vibrio''<br />
**[[3a52]] - ALP + Zn + Mg – ''Shewanella''<br />
**[[3a52]] - ALP + Zn + Mg – ''Shewanella''<br />
-
**[[3q3q]] - ALP + Zn + Ca – ''Sphingomonas''<br />
+
**[[3q3q]] - SpALP + Zn + Ca – ''Sphingomonas''<br />
**[[2yeq]] - ALP D + Fe + Ca – ''Bacillus subtilis''<br />
**[[2yeq]] - ALP D + Fe + Ca – ''Bacillus subtilis''<br />
**[[3zwu]] - PfALP Phox + Fe2O + VO4 – ''Pseudomonas fluorescens''<br />
**[[3zwu]] - PfALP Phox + Fe2O + VO4 – ''Pseudomonas fluorescens''<br />
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**[[5jk4]] - ALP + phosphate - ''Stenotrophomonas maltophilia'' <br />
**[[5jk4]] - ALP + phosphate - ''Stenotrophomonas maltophilia'' <br />
**[[5tj3]] - EmALP + Zn + phosphothreonine – ''Elizabethkingia meningoseptica''<br />
**[[5tj3]] - EmALP + Zn + phosphothreonine – ''Elizabethkingia meningoseptica''<br />
 +
**[[5xwi]] - SpALP + Zn + Ca + phosphothreonine<br />
 +
**[[5xwk]] - SpALP + Zn + Ca + phosphate<br />
*ALP complexes
*ALP complexes
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**[[2mlx]], [[2mly]], [[2mlz]] - EcALP residues 220-310 + trigger factor - NMR<br />
**[[2mlx]], [[2mly]], [[2mlz]] - EcALP residues 220-310 + trigger factor - NMR<br />
**[[5jtl]] – EcALP + SecB<br />
**[[5jtl]] – EcALP + SecB<br />
 +
**[[5jtn]] – EcALP residues 91-145 + SecB<br />
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**[[5jto]] – EcALP residues 271-310 + SecB<br />
**[[5too]] - EmALP (mutant) + Zn <br />
**[[5too]] - EmALP (mutant) + Zn <br />
 +
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:38, 5 March 2019

E. coli alkaline phosphatase dimer with Zn+2 (grey), Mg+2 (green) and phosphate ions, 1elx

Drag the structure with the mouse to rotate

3D Structures of alkaline phosphatase

Updated on 05-March-2019

References

  1. Llinas P, Stura EA, Menez A, Kiss Z, Stigbrand T, Millan JL, Le Du MH. Structural studies of human placental alkaline phosphatase in complex with functional ligands. J Mol Biol. 2005 Jul 15;350(3):441-51. PMID:15946677 doi:http://dx.doi.org/10.1016/j.jmb.2005.04.068
  2. Stec B, Hehir MJ, Brennan C, Nolte M, Kantrowitz ER. Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102. J Mol Biol. 1998 Apr 3;277(3):647-62. PMID:9533886 doi:10.1006/jmbi.1998.1635

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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