6ixp
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Myo2-GTD in complex with Mmr1== | |
| - | + | <StructureSection load='6ixp' size='340' side='right' caption='[[6ixp]], [[Resolution|resolution]] 2.73Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ixp]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixp OCA], [http://pdbe.org/6ixp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixp RCSB], [http://www.ebi.ac.uk/pdbsum/6ixp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixp ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MYO2_YEAST MYO2_YEAST]] Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the delivery of secretory vesicles to sites of active growth during bud emergence and cytokinesis. Required for segregation and inheritance of peroxisomes, late Golgi compartments, mitochondria and the vacuole to the daughter cell during cell division. Also required for correct alignment of the spindle during mitosis.<ref>PMID:10931864</ref> <ref>PMID:11285273</ref> <ref>PMID:11381095</ref> <ref>PMID:11733545</ref> <ref>PMID:11781333</ref> <ref>PMID:12391144</ref> <ref>PMID:12743102</ref> <ref>PMID:21248204</ref> [[http://www.uniprot.org/uniprot/MMR1_YEAST MMR1_YEAST]] Involved in the guiding of mitochondrial tubules to the bud tip during cell division.<ref>PMID:15201867</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Tang, K]] | ||
| + | [[Category: Wei, Z]] | ||
| + | [[Category: Cargo binding domain]] | ||
| + | [[Category: Protein binding]] | ||
| + | [[Category: Protein binding-cell cycle complex]] | ||
Revision as of 07:31, 6 March 2019
Structure of Myo2-GTD in complex with Mmr1
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