Anthrax edema factor

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==3D structures of anthrax edema factor==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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[[1k8t]] - EF adenylate cyclase domain<br />
 
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[[1k93]] - EF adenylate cyclase domain + calmodulin <br />
 
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[[1k90]] - EF adenylate cyclase domain + calmodulin + deoxy-ATP <br />
 
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[[1lvc]] – EF adenylate cyclase domain C terminal + calmodulin + anthraniloyl-deoxy-ATP<br />
 
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[[1pk0]] - EF adenylate cyclase domain C terminal + calmodulin + phosphonylmethoxyethyl-ADP<br />
 
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[[1s26]] - EF adenylate cyclase domain C terminal + calmodulin + methylene-ATP<br />
 
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[[1sk6]] - EF adenylate cyclase domain C terminal + calmodulin + pyrophosphate + cAMP<br />
 
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[[1xfu]] - EF (mutant) + calmodulin<br />
 
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[[1xfv]] - EF + calmodulin + deoxy-ATP<br />
 
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[[1xfw]] - EF + calmodulin + cAMP<br />
 
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[[1xfx]], [[1xfy]], [[1xfz]] - EF + calmodulin
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:36, 12 March 2019

EF trimer (magenta, cyan, salmon) complex with calmodulin (yellow) and adenine diphosphate derivative, Ca+2 (light green) and Yt+3 (green) ions (PDB code 1pk0).

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References

  1. Abrami L, Reig N, van der Goot FG. Anthrax toxin: the long and winding road that leads to the kill. Trends Microbiol. 2005 Feb;13(2):72-8. PMID:15680766 doi:http://dx.doi.org/10.1016/j.tim.2004.12.004
  2. Shen Y, Zhukovskaya NL, Zimmer MI, Soelaiman S, Bergson P, Wang CR, Gibbs CS, Tang WJ. Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3242-7. Epub 2004 Feb 20. PMID:14978283 doi:10.1073/pnas.0306552101

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Michal Harel, Alexander Berchansky

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