4bgi

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==Crystal structure of InhA(S94A) mutant in complex with OH-141==
==Crystal structure of InhA(S94A) mutant in complex with OH-141==
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<StructureSection load='4bgi' size='340' side='right' caption='[[4bgi]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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<StructureSection load='4bgi' size='340' side='right'caption='[[4bgi]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bgi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BGI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bgi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BGI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I4I:3-HYDROXY-N-[(2R,5R,6S,9S,10S,11R)-10-HYDROXY-5,11-DIMETHYL-3,7,12-TRIOXO-2-(PROPAN-2-YL)-9-(PYRIDIN-3-YLMETHYL)-1,4-DIOXA-8-AZACYCLODODECAN-6-YL]PYRIDINE-2-CARBOXAMIDE'>I4I</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I4I:3-HYDROXY-N-[(2R,5R,6S,9S,10S,11R)-10-HYDROXY-5,11-DIMETHYL-3,7,12-TRIOXO-2-(PROPAN-2-YL)-9-(PYRIDIN-3-YLMETHYL)-1,4-DIOXA-8-AZACYCLODODECAN-6-YL]PYRIDINE-2-CARBOXAMIDE'>I4I</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bge|4bge]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bge|4bge]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">inhA, Rv1484, MTCY277.05 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bgi OCA], [http://pdbe.org/4bgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bgi RCSB], [http://www.ebi.ac.uk/pdbsum/4bgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bgi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bgi OCA], [http://pdbe.org/4bgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bgi RCSB], [http://www.ebi.ac.uk/pdbsum/4bgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bgi ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Large Structures]]
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[[Category: Myctu]]
[[Category: Cole, S T]]
[[Category: Cole, S T]]
[[Category: Hartkoorn, R C]]
[[Category: Hartkoorn, R C]]

Revision as of 13:07, 13 March 2019

Crystal structure of InhA(S94A) mutant in complex with OH-141

PDB ID 4bgi

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