Antithrombin

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</StructureSection>
</StructureSection>
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==3D structures of antithrombin==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Antithrombin
 
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**[[1att]] – AT-III – bovine
 
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**[[1ant]], [[2ant]] – hAT – human
 
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**[[1e05]] - hα-AT-III
 
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**[[1e04]] – hβ-AT-III
 
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**[[1ath]], [[2znh]], [[4eb1]] – hAT-III
 
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**[[1dzg]], [[1oyh]], [[1t1f]], [[2beh]], [[2b4x]], [[2hij]] - hAT-III (mutant)
 
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*Antithrombin binary complexes
 
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**[[1azx]], [[1nq9]], [[3evj]], [[1e03]] – hAT III + heparin pentasaccharide
 
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**[[1dzh]] - hAT-III (mutant) + fluorescein
 
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**[[2gd4]] - hAT-III (mutant) + coagulation factor X
 
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**[[1br8]], [[1jvq]], [[1lk6]], [[1r1l]] – hAT-III + peptide
 
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*Antithrombin ternary complexes
 
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**[[1sr5]] - hAT-III + prothrombin + heparin heptasaccharide
 
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**[[1tb6]] - hAT-III (mutant) + thrombin + heparin polysaccharide
 
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**[[2b5t]] - AT-III (mutant) + thrombin (mutant) + heparin polysaccharide
 
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**[[3kcg]] - hAT-III (mutant) + coagulation factor IXa + heparin pentasaccharide
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:57, 18 March 2019

Glycosylated human antithrombin III complex with heparin (in green) (PDB code 3evj)

Drag the structure with the mouse to rotate

References

  1. Li W, Johnson DJ, Esmon CT, Huntington JA. Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat Struct Mol Biol. 2004 Sep;11(9):857-62. Epub 2004 Aug 15. PMID:15311269 doi:10.1038/nsmb811

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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