Monoclonal Antibodies 3D structures
From Proteopedia
(Difference between revisions)
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*Human Fab | *Human Fab | ||
| - | **[[3n9g]], [[3giz]], [[3eo9]], [[1ad9]], [[2fb4]], [[2ig2]], [[1qlr]], [[2zkh]], [[1qbl]], [[1igi]] – hFab mAb - human<br /> | + | **[[3n9g]], [[3giz]], [[3eo9]], [[1ad9]], [[2fb4]], [[2ig2]], [[1qlr]], [[2zkh]], [[1qbl]], [[1igi]], [[5nst]] – hFab mAb - human<br /> |
**[[3qhz]], [[4fql]], [[4gxv]] - hFab anti-influenza<br /> | **[[3qhz]], [[4fql]], [[4gxv]] - hFab anti-influenza<br /> | ||
**[[3qhf]] – hFab anti-influenza (mutant)<br /> | **[[3qhf]] – hFab anti-influenza (mutant)<br /> | ||
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**[[3gk8]], [[1m71]], [[12e8]], [[1yuh]], [[1fgn]], [[1a6t]], [[4isv]], [[4jj5]], [[3gnm]], [[1ae6]], [[3c5s]], [[1mam]], [[3vg0]], [[4kph]], [[1mlb]], [[2vl5]], [[1rmf]], [[2adg]], [[1s5i]], [[1f8t]], [[4dvb]], – mFab <br /> | **[[3gk8]], [[1m71]], [[12e8]], [[1yuh]], [[1fgn]], [[1a6t]], [[4isv]], [[4jj5]], [[3gnm]], [[1ae6]], [[3c5s]], [[1mam]], [[3vg0]], [[4kph]], [[1mlb]], [[2vl5]], [[1rmf]], [[2adg]], [[1s5i]], [[1f8t]], [[4dvb]], – mFab <br /> | ||
**[[3c08]], [[1yy8]] - mFab commercial<br /> | **[[3c08]], [[1yy8]] - mFab commercial<br /> | ||
| - | **[[ | + | **[[6a76]] - mFab anti-ROBO1<br /> |
*Anti-HIV Fab | *Anti-HIV Fab | ||
**[[2pr4]], [[1dfb]], [[3piq]], [[3q6f]], [[3q6g]], [[4xml]] - hFab anti-HIV<br /> | **[[2pr4]], [[1dfb]], [[3piq]], [[3q6f]], [[3q6g]], [[4xml]] - hFab anti-HIV<br /> | ||
| + | **[[3p30]], [[2xra]] – hFab 1281 anti-HIV + gp41 ectodomain<br /> | ||
| + | **[[3ngb]] – hFab anti-HIV + glycoprotein gp120 <br /> | ||
| + | **[[3w9e]] – hFab anti-HIV 2 + glycoprotein D <br /> | ||
**[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - Fab anti-HIV R56 + gp120 - rabbit<br /> | **[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - Fab anti-HIV R56 + gp120 - rabbit<br /> | ||
**[[3cle]], [[3clf]], [[3cmo]], [[1h3p]], [[3oz9]], [[1mf2]], [[1nld]], [[1bog]], [[3mnv]], [[1il1]] - mFab anti-HIV<br /> | **[[3cle]], [[3clf]], [[3cmo]], [[1h3p]], [[3oz9]], [[1mf2]], [[1nld]], [[1bog]], [[3mnv]], [[1il1]] - mFab anti-HIV<br /> | ||
| + | **[[1rzk]] – mFab anti-HIV + glycoprotein gp120 <br /> | ||
**[[3mo1]] - hmFab anti-gp41<br /> | **[[3mo1]] - hmFab anti-gp41<br /> | ||
**[[4ztp]] - rFab anti-HIV R53 - rabbit<br /> | **[[4ztp]] - rFab anti-HIV R53 - rabbit<br /> | ||
| + | **[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - rFab anti-HIV R56 + gp120 <br /> | ||
| + | **[[6did]] – rFab anti-HIV 10A + glycoprotein gp160 <br /> | ||
* Other Fab | * Other Fab | ||
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*Human Fab: protein complex | *Human Fab: protein complex | ||
| - | **[[3iyw]] – hFab mAb + West Nile virus surface protein<br /> | ||
| - | **[[3p30]], [[2xra]] – hFab 1281 anti-HIV + gp41 ectodomain<br /> | ||
**[[3ux9]], [[4z5r]]– hFab anti-interferon + interferon<br /> | **[[3ux9]], [[4z5r]]– hFab anti-interferon + interferon<br /> | ||
**[[2nyy]], [[2nz9]] – hFab + botulinum neurotoxin<br /> | **[[2nyy]], [[2nz9]] – hFab + botulinum neurotoxin<br /> | ||
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**[[4hj0]] – hFab + GIP receptor<br /> | **[[4hj0]] – hFab + GIP receptor<br /> | ||
**[[2vxq]] – hFab + pollen allergen<br /> | **[[2vxq]] – hFab + pollen allergen<br /> | ||
| - | **[[4ubd]], [[5vag]] – hFab + haemagglutinin<br /> | ||
**[[3nfp]], [[3iu3]] – hFab + interleukin-2 receptor<br /> | **[[3nfp]], [[3iu3]] – hFab + interleukin-2 receptor<br /> | ||
**[[2xqb]], [[4g6j]], [[4g6m]] - hFab + interleukin<br /> | **[[2xqb]], [[4g6j]], [[4g6m]] - hFab + interleukin<br /> | ||
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**[[1iqd]] – hFab BO2C11 + human factor VIII<br /> | **[[1iqd]] – hFab BO2C11 + human factor VIII<br /> | ||
**[[1nlo]] - hFab anti-factor IX + factor IX<br /> | **[[1nlo]] - hFab anti-factor IX + factor IX<br /> | ||
| - | **[[2ghw]] - hFab anti-SARS + SARS spike protein<br /> | ||
| - | **[[3ngb]] – hFab anti-HIV + glycoprotein gp120 <br /> | ||
| - | **[[3w9e]] – hFab anti-HIV 2 + glycoprotein D <br /> | ||
**[[3skj]] – hFab + ephrin type-A receptor<br /> | **[[3skj]] – hFab + ephrin type-A receptor<br /> | ||
**[[4dtg]] – hFab 2021 + tissue factor pathway inhibitor<br /> | **[[4dtg]] – hFab 2021 + tissue factor pathway inhibitor<br /> | ||
**[[4k7p]] – hFab RHUMAB6 + mFab 10C4<br /> | **[[4k7p]] – hFab RHUMAB6 + mFab 10C4<br /> | ||
**[[5xf1]], [[5xez]] – hFab + glucagon receptor<br /> | **[[5xf1]], [[5xez]] – hFab + glucagon receptor<br /> | ||
| - | **[[ | + | |
| + | *Human Fab: viral protein complex | ||
| + | |||
| + | **[[6nn3]] – hFab + VP2 of parvovirus<br /> | ||
| + | **[[6iw0]], [[6iw2]], [[6ivz]] – hFab + yellow fever E protein <br /> | ||
| + | **[[3iyw]] – hFab mAb + West Nile virus surface protein<br /> | ||
| + | **[[4ubd]], [[5vag]] – hFab + influenza virus haemagglutinin<br /> | ||
| + | **[[2ghw]] - hFab anti-SARS + SARS spike protein<br /> | ||
*Mouse Fab: protein complex | *Mouse Fab: protein complex | ||
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**[[3kj4]] – mFab 1D9 + reticulon-4 receptor<br /> | **[[3kj4]] – mFab 1D9 + reticulon-4 receptor<br /> | ||
**[[3ncy]] – mFab + arginine agmatine antiporter<br /> | **[[3ncy]] – mFab + arginine agmatine antiporter<br /> | ||
| - | **[[4lvh]], [[1qfu]] – mFab + haemagglutinin<br /> | ||
**[[2zch]], [[2zcl]] – mFab 8G8F5 + PSA<br /> | **[[2zch]], [[2zcl]] – mFab 8G8F5 + PSA<br /> | ||
**[[2vc2]], [[2vdk]], [[2vdl]], [[2vdm]], [[2vdn]], [[5hdb]] - mFab + integrin<br | **[[2vc2]], [[2vdk]], [[2vdl]], [[2vdm]], [[2vdn]], [[5hdb]] - mFab + integrin<br | ||
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**[[3d9a]], [[1bql]], [[1fbi]], [[2iff]], [[1fdl]], [[3hfm]], [[1c08]], [[1dqj]], [[1nby]], [[1nbz]], [[1ndg]], [[1ndm]], [[1p2c]], [[1ua6]], [[1uac]], [[1xgp]], [[1xgq]], [[1yqv]], [[1mlc]], [[1kip]], [[1kiq]], [[1kir]] – mFab HYHEL + lysozyme<br /> | **[[3d9a]], [[1bql]], [[1fbi]], [[2iff]], [[1fdl]], [[3hfm]], [[1c08]], [[1dqj]], [[1nby]], [[1nbz]], [[1ndg]], [[1ndm]], [[1p2c]], [[1ua6]], [[1uac]], [[1xgp]], [[1xgq]], [[1yqv]], [[1mlc]], [[1kip]], [[1kiq]], [[1kir]] – mFab HYHEL + lysozyme<br /> | ||
**[[1ic4]], [[1ic5]], [[1ic7]], [[1j1p]], [[1j1o]], [[1j1x]], [[2dqc]], [[2dqd]], [[2dqe]], [[2dqf]], [[2dqg]], [[2dqh]], [[2dqi]], [[2dqj]], [[3a67]], [[3a6b]], [[3a6c]] - mFab HYHEL10 (mutant) + lysozyme<br /> | **[[1ic4]], [[1ic5]], [[1ic7]], [[1j1p]], [[1j1o]], [[1j1x]], [[2dqc]], [[2dqd]], [[2dqe]], [[2dqf]], [[2dqg]], [[2dqh]], [[2dqi]], [[2dqj]], [[3a67]], [[3a6b]], [[3a6c]] - mFab HYHEL10 (mutant) + lysozyme<br /> | ||
| - | **[[3i50]], [[1ztx]] – mFab E53 + West Nile virus envelope glycoprotein<br /> | ||
| - | **[[2r29]], [[4l5f]] – mFab + Dengue envelope glycoprotein<br /> | ||
| - | **[[3fmg]] - mFab 4F8 + Simian rotavirus glycoprotein VP7<br /> | ||
| - | **[[3j1s]] – mFab A20 + adeno-associated virus capsid protein Vp1<br /> | ||
| - | **[[1rzk]] – mFab anti-HIV + glycoprotein gp120 <br /> | ||
| - | **[[2xqy]] - mFab anti-pseudorabies virus + glycoprotein H <br /> | ||
**[[4aei]] - mFab anti-AAHI + scorpion toxin<br /> | **[[4aei]] - mFab anti-AAHI + scorpion toxin<br /> | ||
**[[4ag4]] - mFab + DDR1<br /> | **[[4ag4]] - mFab + DDR1<br /> | ||
**[[4f37]] – mFab anti-amyloid-β + colicin E7<br /> | **[[4f37]] – mFab anti-amyloid-β + colicin E7<br /> | ||
**[[3gi8]], [[3gi9]] – mFab 7F11 + APCT transporter<br /> | **[[3gi8]], [[3gi9]] – mFab 7F11 + APCT transporter<br /> | ||
| + | **[[6cse]] – mFab + AGCS symporter + Ala<br /> | ||
**[[3ffd]] – mFab + parathyroid hormone-related protein<br /> | **[[3ffd]] – mFab + parathyroid hormone-related protein<br /> | ||
**[[2zuq]] – mFab + disulfide bond formation protein<br /> | **[[2zuq]] – mFab + disulfide bond formation protein<br /> | ||
| - | **[[3bgf]], [[4f2m]] – mFab + spike protein<br /> | ||
**[[2zjs]] – mFab 56 + preprotein translocase SecYE<br /> | **[[2zjs]] – mFab 56 + preprotein translocase SecYE<br /> | ||
**[[2j88]] – mFab + hyaluronidase<br /> | **[[2j88]] – mFab + hyaluronidase<br /> | ||
**[[4f9l]], [[4f9p]] – mFab anti-BTN3A1 + butyrophilin A1<br /> | **[[4f9l]], [[4f9p]] – mFab anti-BTN3A1 + butyrophilin A1<br /> | ||
| - | **[[1qfu]] - mFab + hemagglutinin<br /> | ||
**[[1wej]] – mFab E8 + cytochrome C<br /> | **[[1wej]] – mFab E8 + cytochrome C<br /> | ||
**[[2j4w]], [[2j5l]] – mFab + apical membrane antigen<br /> | **[[2j4w]], [[2j5l]] – mFab + apical membrane antigen<br /> | ||
| - | **[[ | + | **[[2nr6]], [[5vyf]] – mFab + allergen <br /> |
| - | + | ||
| - | + | ||
**[[2hlf]], [[2ht2]], [[2ht3]], [[2ht4]], [[2htk]], [[2htl]], [[2h2p]], [[2h2s]], [[2exw]], [[2exy]], [[2fee]], [[1ots]] – mFab + exchange transporter ClCA<br /> | **[[2hlf]], [[2ht2]], [[2ht3]], [[2ht4]], [[2htk]], [[2htl]], [[2h2p]], [[2h2s]], [[2exw]], [[2exy]], [[2fee]], [[1ots]] – mFab + exchange transporter ClCA<br /> | ||
**[[2ez0]], [[2fec]], [[2fed]], [[1ott]], [[1otu]] - mFab + exchange transporter ClCA (mutant)<br /> | **[[2ez0]], [[2fec]], [[2fed]], [[1ott]], [[1otu]] - mFab + exchange transporter ClCA (mutant)<br /> | ||
| - | **[[2aep]], [[2aeq]], [[1nma]], [[1nmb]], [[1nmc]] – mFab + neuraminidase<br /> | ||
**[[1z3g]] – mFab 2A8 + ookinete surface protein<br /> | **[[1z3g]] – mFab 2A8 + ookinete surface protein<br /> | ||
**[[1fj1]], [[1osp]] – mFab + outer surface protein<br /> | **[[1fj1]], [[1osp]] – mFab + outer surface protein<br /> | ||
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**[[3nid]], [[3nif]], [[3nig]], [[3t3m]], [[3t3p]], [[3v4p]], [[3v4v]] – mFab 10E5 + integrin<br /> | **[[3nid]], [[3nif]], [[3nig]], [[3t3m]], [[3t3p]], [[3v4p]], [[3v4v]] – mFab 10E5 + integrin<br /> | ||
**[[3v6o]] – mFab + leptin receptor<br /> | **[[3v6o]] – mFab + leptin receptor<br /> | ||
| - | **[[4etq]] – mFab anti-vaccinia + IMV membrane protein<br /> | ||
**[[5tr1]], [[5tqq]] - mFab + Cl channel<br /> | **[[5tr1]], [[5tqq]] - mFab + Cl channel<br /> | ||
**[[5t5f]] - mFab JAR5 + factor H binding protein<br /> | **[[5t5f]] - mFab JAR5 + factor H binding protein<br /> | ||
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**[[5dlm]] - mFab + matrix protein 2<br /> | **[[5dlm]] - mFab + matrix protein 2<br /> | ||
**[[4zyp]] – mFab + fusion protein F0<br /> | **[[4zyp]] – mFab + fusion protein F0<br /> | ||
| + | **[[6a77]], [[6a78]] - mFab anti-ROBO1 + roundabout homolog<br /> | ||
| + | **[[6a79]] - mFab anti-ROBO1 (mutant) + roundabout homolog<br /> | ||
| + | |||
| + | *Mouse Fab: viral protein complex | ||
| + | |||
| + | **[[4lvh]], [[1qfu]] – mFab anti-influenza haemagglutinin<br /> | ||
| + | **[[2aep]], [[2aeq]], [[1nma]], [[1nmb]], [[1nmc]] – mFab + influenza virus neuraminidase<br /> | ||
| + | **[[3i50]], [[1ztx]] – mFab E53 + West Nile virus envelope glycoprotein<br /> | ||
| + | **[[2r29]], [[4l5f]] – mFab + Dengue envelope glycoprotein<br /> | ||
| + | **[[3fmg]] - mFab 4F8 + Simian rotavirus glycoprotein VP7<br /> | ||
| + | **[[3j1s]] – mFab A20 + adeno-associated virus capsid protein Vp1<br /> | ||
| + | **[[2xqy]] - mFab anti-pseudorabies virus + glycoprotein H <br /> | ||
| + | **[[3bgf]], [[4f2m]] – mFab + coronavirus spike protein<br /> | ||
| + | **[[3v7a]] - mFab + norovirus capsid protein<br /> | ||
| + | **[[2i9l]] – mFab + vaccinia virus protein<br /> | ||
| + | **[[4etq]] – mFab anti-vaccinia + IMV membrane protein<br /> | ||
*Other Fab: protein complex | *Other Fab: protein complex | ||
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**[[1bj1]], [[2vwe]] - hmFab + VEGF<br /> | **[[1bj1]], [[2vwe]] - hmFab + VEGF<br /> | ||
**[[3uaj]], [[3uc0]] – Fab + envelope protein - chimpanzee<br /> | **[[3uaj]], [[3uc0]] – Fab + envelope protein - chimpanzee<br /> | ||
| - | **[[4jo1]], [[4jo2]], [[4jo3]], [[4jo4]] - rFab anti-HIV R56 + gp120 <br /> | ||
**[[3b9k]] – rFab + CD8<br /> | **[[3b9k]] – rFab + CD8<br /> | ||
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**[[2hmi]], [[1n5y]], [[1n6q]], [[1r0a]], [[1hys]] – mFab 28 + reverse transcriptase + DNA<br /> | **[[2hmi]], [[1n5y]], [[1n6q]], [[1r0a]], [[1hys]] – mFab 28 + reverse transcriptase + DNA<br /> | ||
**[[3klh]] – mFab + P66 RT + P51 RT + DNA<br /> | **[[3klh]] – mFab + P66 RT + P51 RT + DNA<br /> | ||
| - | **[[3w11]], [[3w12]], [[3w13]], [[4oga]], [[5kqv]] – mFab + insulin + insulin receptor<br /> | + | **[[3w11]], [[3w12]] , [[3w13]] , [[3w14]], [[4oga]], [[5kqv]] – mFab + insulin + insulin receptor<br /> |
**[[1t03]] - mFab + Pol polyprotein + DNA<br /> | **[[1t03]] - mFab + Pol polyprotein + DNA<br /> | ||
**[[1xcq]], [[1xct]], [[1xf5]] - mFab + capsid C + protein L<br /> | **[[1xcq]], [[1xct]], [[1xf5]] - mFab + capsid C + protein L<br /> | ||
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**[[3j70]] – hFab + gp41 + gp120 + CD4<br /> | **[[3j70]] – hFab + gp41 + gp120 + CD4<br /> | ||
**[[4mxw]] – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3<br /> | **[[4mxw]] – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3<br /> | ||
| + | **[[6mid]] – hFab + zika E protein + zika M protein<br /> | ||
*Full Immunoglobulin | *Full Immunoglobulin | ||
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*Catalytic antibody | *Catalytic antibody | ||
| - | **[[1kn2]], [[1kn4]], [[1yei]], [[1yej]], [[1yek]], [[1ngw]], [[1ngx]], [[1ngy]], [[1ngz]], [[1ct8]], [[2gfb]], [[1lo0]], [[1lo2]], [[1lo3]], [[1lo4]], [[1um4]], [[1um5]], [[1um6]], [[2gjz]], [[2gk0]], [[1f3d]], [[1ru9]], [[1rua]], [[1ruk]], [[1rul]], [[1rum]], [[1rup]], [[1ruq]], [[1rur]], [[2aju]], [[15c8]], [[2rcs]], [[1hq4]], [[1cf8]], [[1kem]], [[1yeh]], [[1yec]], [[1yed]], [[1yee]], [[1eap]], [[3bd3]], [[3bd4]], [[3bd5]], [[1jgu]], [[1jgv]], [[3cle]], [[3clf]] – mFab <br /> | + | **[[1kn2]], [[1kn4]], [[1yei]], [[1yej]], [[1yek]], [[1ngw]], [[1ngx]], [[1ngy]], [[1ngz]], [[1ct8]], [[2gfb]], [[1lo0]], [[1lo2]], [[1lo3]], [[1lo4]], [[1um4]], [[1um5]], [[1um6]], [[2gjz]], [[2gk0]], [[1f3d]], [[1ru9]], [[1rua]], [[1ruk]], [[1rul]], [[1rum]], [[1rup]], [[1ruq]], [[1rur]], [[2aju]], [[15c8]], [[2rcs]], [[1hq4]], [[1cf8]], [[1kem]], [[1yeh]], [[1yec]], [[1yed]], [[1yee]], [[1eap]], [[3bd3]], [[3bd4]], [[3bd5]], [[1jgu]], [[1jgv]], [[3cle]], [[3clf]], [[5xqw]], [[5i0z]] – mFab <br /> |
**[[1fl6]], [[1fl5]] – mFab 28B4 (mutant)<br /> | **[[1fl6]], [[1fl5]] – mFab 28B4 (mutant)<br /> | ||
**[[1mie]], [[1mj8]], [[1mju]], [[43c9]] – mFab esterolytic<br /> | **[[1mie]], [[1mj8]], [[1mju]], [[43c9]] – mFab esterolytic<br /> | ||
Revision as of 09:13, 19 March 2019
3D structures of Monoclonal Antibodies
Updated on 19-March-2019
Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
