Arginase
From Proteopedia
(Difference between revisions)
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The manganese ions are located at the bottom of a 15A cleft. <scene name='59/593950/Cv/4'>Active site</scene>. The proposed reaction mechanism involves <scene name='59/593950/Cv/5'>H141, D128, E277</scene> in rat.<ref>PMID:11258880</ref> | The manganese ions are located at the bottom of a 15A cleft. <scene name='59/593950/Cv/4'>Active site</scene>. The proposed reaction mechanism involves <scene name='59/593950/Cv/5'>H141, D128, E277</scene> in rat.<ref>PMID:11258880</ref> | ||
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| + | ==3D structures of arginase== | ||
| + | [[Arginase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[1wvb]] – hArg 1 (mutant) + Mn <br /> | **[[1wvb]] – hArg 1 (mutant) + Mn <br /> | ||
**[[1cev]], [[2cev]] – BcArg + Mn – ''Bacillus caldovelox''<br /> | **[[1cev]], [[2cev]] – BcArg + Mn – ''Bacillus caldovelox''<br /> | ||
| + | **[[6dkt]] – BsArg + Mn – ''Bacillus subtilis''<br /> | ||
| + | **[[6nbk]] – Arg + Mn – ''Bacillus cereus''<br /> | ||
**[[4g3h]] – Arg + Mn – ''Helicobacter pylori''<br /> | **[[4g3h]] – Arg + Mn – ''Helicobacter pylori''<br /> | ||
**[[4ity]] – LmArg + Mn – ''Leishmania mexicana''<br /> | **[[4ity]] – LmArg + Mn – ''Leishmania mexicana''<br /> | ||
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**[[4gsz]] – hArg 1 + Zn + Arg analog<br /> | **[[4gsz]] – hArg 1 + Zn + Arg analog<br /> | ||
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| + | *Mg containing arginase | ||
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| + | **[[6nfp]] – BsArg + Mg<br /> | ||
*Mn and Zn containing arginase | *Mn and Zn containing arginase | ||
Revision as of 11:25, 19 March 2019
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3D structures of arginase
Updated on 19-March-2019
References
- ↑ Dowling DP, Di Costanzo L, Gennadios HA, Christianson DW. Evolution of the arginase fold and functional diversity. Cell Mol Life Sci. 2008 Jul;65(13):2039-55. doi: 10.1007/s00018-008-7554-z. PMID:18360740 doi:http://dx.doi.org/10.1007/s00018-008-7554-z
- ↑ Cox JD, Cama E, Colleluori DM, Pethe S, Boucher JL, Mansuy D, Ash DE, Christianson DW. Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry. 2001 Mar 6;40(9):2689-701. PMID:11258880
