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6fu0

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m (Protected "6fu0" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6fu0 is ON HOLD
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==Phosphotriesterase PTE_A53_4==
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<StructureSection load='6fu0' size='340' side='right'caption='[[6fu0]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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Authors: Dym, O., Aggarwal, N., Albeck, S., Unger, T., Hamer Rogotner, S., Silman, I., Leader, H., Ashani, Y., Goldsmith, M., Greisen, P., Tawfik, D., Sussman, L.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6fu0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FU0 FirstGlance]. <br>
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Description: Phosphotriesterase PTE_A53_4
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fee|6fee]], [[6fef|6fef]], [[6fei|6fei]], [[6fev|6fev]], [[6ffw|6ffw]], [[6for|6for]], [[6frz|6frz]], [[6fqe|6fqe]], [[6fs3|6fs3]]</td></tr>
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[[Category: Leader, H]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
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[[Category: Sussman, L.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fu0 OCA], [http://pdbe.org/6fu0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fu0 RCSB], [http://www.ebi.ac.uk/pdbsum/6fu0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fu0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/OPD_BREDI OPD_BREDI]] Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
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__TOC__
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</StructureSection>
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[[Category: Aryldialkylphosphatase]]
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[[Category: Large Structures]]
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[[Category: Aggarwal, N]]
[[Category: Albeck, S]]
[[Category: Albeck, S]]
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[[Category: Unger, T]]
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[[Category: Ashani, Y]]
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[[Category: Aggarwal, N]]
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[[Category: Dym, O]]
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[[Category: Goldsmith, M]]
[[Category: Greisen, P]]
[[Category: Greisen, P]]
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[[Category: Goldsmith, M]]
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[[Category: Leader, H]]
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[[Category: Hamer Rogotner, S]]
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[[Category: Rogotner, S Hamer]]
[[Category: Silman, I]]
[[Category: Silman, I]]
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[[Category: Sussman, L J]]
[[Category: Tawfik, D]]
[[Category: Tawfik, D]]
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[[Category: Ashani, Y]]
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[[Category: Unger, T]]
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[[Category: Dym, O]]
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[[Category: Hydrolase]]
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[[Category: Metalloenzyme]]
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[[Category: Tim barrel]]

Revision as of 07:51, 20 March 2019

Phosphotriesterase PTE_A53_4

PDB ID 6fu0

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